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Enhanced acid stability of a reduced nicotinamide adenine dinucleotide (NADH) analogue

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Abstract

A methyl substituent at C-5 of the nicotinamide ring is found to confer increased acid stability in a reduced nicotinamide model (5-20 fold) and in a reduced dinucleotide coenzyme (2-3 fold), while retaining reactivity towards hydride transfer

Topics: QD
Publisher: ROYAL SOC CHEMISTRY
OAI identifier: oai:wrap.warwick.ac.uk:11650
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