[[abstract]] Visiting museums is an extensive and systematical form of informal learning. Many issues can be observed in the currently available research studies and improvement is needed in the related fields. For instance, the level of interaction between visitors and exhibits are insufficient, mobile guiding systems should be able to promote visitors’ motivation more effectively, and evaluating methods to the effects of mobile guiding systems ought to be more rigorous. This study developed a game-based mobile guiding system in order to examine the difference between the learning effects of using mobile guiding system and traditional paper guidebook. The effects of cooperative game-based guiding system on visiting activities were also studied. The research developed a mobile guiding system and applied it on the “Tang Dynasty Tri-Color Glazed Pottery” exhibition in the National Museum of History. The participants included two classes of students in the Department of Adult and Continuing Education of National Taiwan Normal University. There were two experimental groups: 15 students in the group of cooperative learning mode and 16 students in the group of individual learning mode. The control group included 15 students. The students in the group of cooperative learning mode were divided into teams of three and used the game-based guiding system during their visits in the museum. On the other hand, the students in the group of individual learning mode used the same game-based guiding system, but were not allowed to talk to other participants. The control group used the traditional paper guidebook. Each student’s visiting process was video taped. This study also collected the pre- and the post-test knowledge scores of Tang Dynasty Tri-Color Glazed Pottery. The pre- and the post-attitudinal questionnaires were implemented as well. These data were then compared and analyzed in the study. The results indicate that students using the mobile guiding system in the two experimental groups (including the cooperative learning mode as well as the individual learning mode) spend more time on interacting to the exhibits, as compared to the students who use traditional paper guidebook. However, there is no significantly difference among the groups in promoting knowledge and interest on Tang Dynasty Tri-Color Glazed Pottery.