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Catalytic asymmetric conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones

By Pieter H. Bos, Beatriz Maciá, M. Ángeles Fernández-Ibáñez, Adriaan J. Minnaard and Ben L. Feringa

Abstract

An efficient method is reported for the highly enantioselective copper-catalyzed conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones using a monodentate phosphoramidite ligand.

Year: 2010
OAI identifier: oai:ub.rug.nl:dbi/4b4f1bf330013
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