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New insight in haloalkane dehalogenase kinetics and evolution by enzyme engineering

By Mariël Gertrude Pikkemaat

Abstract

Halogenated carbon compounds represent a major class of recalcitrant environmental pollutants. Even for many of these often xenobiotic chemicals, however, the highly dynamic and adaptive microbial world has managed to develop suitable degradation pathways. A particular critical step in the degradation pathway of organohalogens appears to be the cleavage of carbon-halogen bonds. ... Zie: Summary.

Topics: Protein engineering, Haloalkaan dehalogenase; Moleculaire dynamica; Proefschriften (vorm); nucleïnezuren; eiwitten; vitaminen (biochemie); hormonen; enzymen
Year: 2004
OAI identifier: oai:ub.rug.nl:dbi/4b1ccf517327f
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