Inhibition of the inflammatory response initiated during cardiopulmonary bypass

Abstract

Cardiopulmonary bypass (CPB), a supporting system to permit open-hears surgery, generates a whole body inflammatory response leading to the so called "postperfusion syndrome". Although the typical case suffering from hemorrhagic pumonary edema is nowadays rarely seen, the employment of CPB still exposes patients to the increased capillary permeability, increased interstitial fluid accumulation, and reduced organ function, resulting in a delay in postoperative recovery. ... Zie: Summary