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Sinusiodal efflux of organic anions in the liver.

By Henricus Martinus Joseph Nijssen


This thesis deals with the sinusoidal efflux of the organic anionic model compound dibromosulfophthalein (DBSP) in the liver. Sinusoidal efflux is the process of net substrate transport from the liver cell into the general circulation. The mechanisms of this process have been little studied until now. Many xenobiotics that are primarily taken up by the liver are (after possible metabolism to anionic conjugates) to a large extend secreted into the general circulation. Zie: Summary

Topics: Lever, Xenobiotica, Stoftransport, Anionen, Proefschriften (vorm); gastro-enterologie
Year: 1991
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