In this thesis, the results of a series of investigations into the barrier function of human skin are presented. In these investigations, the barrier function was assessed by water vapour loss measurements of the skin using a method based on gradient estimation. The aim of this thesis is to study the role and efficiency of motor control and anticipation processes in the development of children with and without disturbances in the motor system. Chapter I is a general introduction to the subject of this thesis. In the first part of this chapter the rationale for extending knowledge in the field of motor development is given. Generally, it is found that motor development and disturbances in the motor system are manifest in the speed and accuracy of goal directed movements. The question is what processes determine speed and accuracy of such responses, and how they contribute to the ontogeny of skilled motor performance? ... Zie: Summary
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