Location of Repository

Doença de Mucha-Habermann úlceronecrótica febril em adulto com boa resposta à corticoterapia oral Febrile ulceronecrotic Mucha-Habermann disease in adult patient successfully treated with systemic corticosteroid

By Priscila Wolf Nassif, Deise Aparecida Santos Godoy, Sadamitsu Nakandakari, Cinthia Janine Meira Alves and Cleverson Teixeira Soares

Abstract

A doença de Mucha-Habermann ulceronecrótica febril (FUMHD) é uma variante clínica rara da pitiríase liquenoide variceliforme aguda (PLEVA). Tem etiologia incerta e é caracterizada por lesões úlceronecróticas, associadas a sintomas sistêmicos. Relata-se um caso de paciente masculino, com início agudo de lesões máculo-papulares, vesicobolhosas e úlceronecróticas, associadas à febre alta e mialgia. Tratado com prednisona 0,5 mg/kg/dia, obteve-se excelente resposta terapêutica. A FUMHD é uma variante severa da PLEVA, cujo diagnóstico é clínico e histopatológico. Vários tratamentos são descritos, tais como: metrotexate, corticoesteroides, PUVA, mas nenhum foi estabelecido.<br>The Febrile Ulceronecrotic Mucha-Habermann (FUMHD) disease is a rare variant of pityriasis lichenoides et varioliformis acuta (PLEVA). Its etiology still remains unknown and it is characterized by a sudden onset of ulceronecrotic skin lesions associated with systemic symptons. It is reported here the case of a male patient with a sudden and acute evolution of macules and papules, ulceronecrotic and vesicle-bullous lesions associated with systemic symptons. The patient was treated with prednisone 0,5 mg/kg/day with a dramatic response. The FUMHD is a severe variant of PLEVA and its diagnosis is clinical and histopathological. Many treatments such as methotrexate, corticosteroids and PUVA have been described .However, none of them has been settled

Topics: Corticosteroides, Pitiríase liquenoide, Vasculite, Adrenal cortex hormones, Pityriasis lichenoides, Vasculitis, Dermatology, RL1-803, Medicine, R, DOAJ:Dermatology, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: Sociedade Brasileira de Dermatologia
Year: 2010
DOI identifier: 10.1590/S0365-05962010000600018
OAI identifier: oai:doaj.org/article:99c593d6b5864ab08eb5d3181f5e2239
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/1806-4841 (external link)
  • https://doaj.org/toc/0365-0596 (external link)
  • http://www.scielo.br/scielo.ph... (external link)
  • https://doaj.org/article/99c59... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.