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Modelling of L-valine Repeated Fed-batch Fermentation Process Taking into Account the Dissolved Oxygen Tension

By Tzanko Georgiev, Ignat Dimov, Kalin Todorov, Julia Kristeva and Alexander Ratkov

Abstract

This article deals with synthesis of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-valine production. The presented approach of the investigation includes the following main procedures: description of the process by generalized stoichiometric equations; preliminary data processing and calculation of specific rates for main kinetic variables; identification of the specific rates takes into account the dissolved oxygen tension; establishment and optimisation of dynamic model of the process; simulation researches. MATLAB is used as a research environment

Topics: Modelling, Optimisation, Repeated fed-batch process, Fed-batch process with droppings, L-valine., Biology (General), QH301-705.5, Science, Q, DOAJ:Biology, DOAJ:Biology and Life Sciences, Medicine (General), R5-920, Medicine, R, DOAJ:Medicine (General), DOAJ:Health Sciences, Biotechnology, TP248.13-248.65, Chemical technology, TP1-1185, Technology, T, DOAJ:Biotechnology, DOAJ:Life Sciences, Computer applications to medicine. Medical informatics, R858-859.7
Publisher: Academic Publishing House
Year: 2009
OAI identifier: oai:doaj.org/article:f3f14efe6b6d49e3814ea3359a677041
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