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Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation

By Kanthilatha Pai, Pratap Kumar and Akhila Vasudeva


Placental site trophoblastic tumour (PSTT) is the least common form of gestational trophoblastic neoplasia accounting for only 1-2% of trophoblastic tumors. Approximately 200 cases are reported in English literature. PSTT presenting as a cervical growth is even less common. Differentiation of PSTT from other types of GTN, non-neoplastic gestational trophoblastic disease and non-trophoblastic tumors is important clinically due to differences in their therapeutic approaches.Appreciation of the morphologic features and immunophenotype allows their accurate diagnosis.Although most of the cases of PSTT behave in a benign fashion,the clinical behavior of PSTT can sometimes be variable and several prognostic factors can help to predict the biological behavior of this condition. We report a rare case of placental site trophoblastic tumor, presenting as a cervical mass, in a 38 year old female, and review the literature. [J Interdiscipl Histopathol 2013; 1(5.000): 286-289

Topics: Gestational trophoblastic disease, Placental site trophoblastic tumor, Cervical, Medicine (General), R5-920, Medicine, R, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: eJManager Publishing
Year: 2013
DOI identifier: 10.5455/jihp.20130723051544
OAI identifier: oai:doaj.org/article:14e53b544e4244fa8b93a76a7deb50ff
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