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Imiquimod 5% cream in the treatment of superficial and nodular basal cell carcinomas: study of 10 cases Tratamento tópico do carcinoma basocelular superficial e nodular pelo imiquimod creme a 5%: observação de 10 casos

By Cyro Festa Neto

Abstract

BACKGROUND: Topical treatment with 5% imiquimod cream has been demonstrated to be effective in patients with basal cell carcinoma. OBJECTIVES: In the present study, efficacy and tolerability of this treatment was analyzed in 10 patients with 13 different types of superficial and nodular basal cell carcinomas. METHODS: Imiquimod cream was applied daily for a mean period of 23 days. RESULTS AND CONCLUSIONS: All patients responded favorably to the drug with healing of the lesions. No recurrence was observed during two to three months of follow up.<br>FUNDAMENTOS: O uso tópico do imiquimod 5% em creme para o tratamento de carcinomas basocelulares tem-se mostrado eficaz. OBJETIVOS: Com base nesse fato o autor analisa a efetividade e tolerabilidade desse método em 10 doentes com 13 carcinomas basocelulares dos tipos superficial e nodular. MÉTODOS: As aplicações foram diárias, e o número médio de dias de tratamento foi 23. RESULTADOS E CONCLUSÕES: Todos os doentes responderam à medicação com desaparecimento das lesões e são seguidos a cada dois ou três meses, até o momento sem recidiva do quadro

Topics: adjuvantes imunológicos, carcinoma basocelular, adjuvants, immunologic, carcinoma, basal cell, Dermatology, RL1-803, Medicine, R, DOAJ:Dermatology, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: Sociedade Brasileira de Dermatologia
Year: 2002
DOI identifier: 10.1590/S0365-05962002000600006
OAI identifier: oai:doaj.org/article:2b9e1dcfdfbc4e06a45346579799db65
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