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‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a Silver(I)-Catalyzed Cascade Approach

By Jian Li, Hong Liu, Qingya Kong, Hualiang Jiang, Yu Zhou and Baifeng Jiang

Abstract

An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO3 catalyzed ‘one-pot’ cascade process involving formation of two new C–N bonds and one new C–O bond

Topics: silver, one-pot, cascade transformation, isoquinolines, heterocyclic molecule, Organic chemistry, QD241-441, Chemistry, QD1-999, Science, Q, DOAJ:Organic Chemistry, DOAJ:Chemistry
Publisher: MDPI AG
Year: 2013
DOI identifier: 10.3390/molecules18010814
OAI identifier: oai:doaj.org/article:29e8d1728e1741508c39ff5e203c49d9
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