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A prospective study with children whose mothers had dengue during pregnancy Estudo prospectivo com lactentes cujas mães tiveram dengue durante a gravidez

By Luiz Tadeu Moraes Figueiredo, Rita Helena Carlucci and Geraldo Duarte

Abstract

Dengue congenital disease was not confirmed in 10 children whose mothers had the infection during pregnancy. The fetal sera presented anti-dengue IgG antibodies which progressively declined, and disappeared after 8 months. IgM antibodies to dengue were not observed in the sera. Other normal data suggesting the healthy state of the children included: absence of malformations, pregnancy time, Apgar index, weight, and placenta aspect<br>Num estudo sobre doença congênita, com 10 lactentes de mães que tiveram dengue na gravidez, nao se detectou infecção intra-uterina. Os soros fetais apresentaram anticorpos IgG contra dengue tipo 1, por teste imuno-enzimático, provavelmente transferidos passivamente. Estes anticorpos, analisados de forma prospectiva em 8 casos, foram declinando progressivamente, até desaparecerem, aos 8 meses de idade. Anticorpos do tipo IgM contra dengue nao foram detectados. O tempo gestacional normal, os índices de Apgar, o peso e as placentas normais dos neonatos, bem como a ausência de malformações, foram evidências contrárias à infecção intra-uterina

Topics: Dengue, Infecção na gestação, Doença na gestação, Medicine (General), R5-920, Medicine, R, DOAJ:Medicine (General), DOAJ:Health Sciences, Arctic medicine. Tropical medicine, RC955-962
Publisher: Universidade de São Paulo
Year: 1994
DOI identifier: 10.1590/S0036-46651994000500005
OAI identifier: oai:doaj.org/article:49d32f6bcd754ffb9050e9036c573db9
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