Perinatall mortality is fetus mortality in pregnancy age of > 28 weeks up to and including the first 7 days after child birth. Perinatal mortality is the main cause of infant mortality. This research aims to know how much the risk of prenatal mortality of mother with low quality of Antenatal Care after considering the factors of the mother, the infant and health services. Design of the study is case control and the numbers of samples are 95 cases and 95 controls. The result of study indicates that the proportion of respondent’s adequate good quality of Antenatal Care at cases group is 52.6 %, it is less than control group 86.3 %. The characteristics of mothers are: 23.7 % are ≥ 35 years old, 43.7 % were paritas once, 51.05 % under and have graduated from elementary school, 20.5 % were abnormal childbirth and 7.4 % had previous diseases. The characteristics of the infants are: 26.8 % were low weight birth, 28.4 % were asfiction, 4.2 % were infected and 8.4 % were congenital deviation. While from the childbirth guides indicate that 16.3 % were helped by non health official and 54.2 % were suggested by midwives to give birth in hospitals. The value of crude odds ratio of the infants born by the mothers inadequate Antenatal Care, had the risk of prenatal mortality 5.6 times compared to the mothers adequate Antenatal Care (95 % C.I 2.054- 11.592, p< 0.001). After controlled to the variables of child birth condition, low weight birth and the asfixia, it indicates the value of adjusted odds ratio of the infants born by the mothers inadequate antenatal care had the risk to get perinatal mortality 4.88 times compared to the mothers adequate antenatal care ( p < 0.001). The suggestion for Health Office of Banyumas Regency are to increase the best antenatal care quality, both in frequent and in providing the equipments and also by screening to bear child for the possibilities of chronic disease indication or congenital deviations
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