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Η ΑΞΙΑ ΤΟΥ ΠΡΟΣΔΙΟΡΙΣΜΟΥ ΤΩΝ ΙΣΟΕΝΖΥΜΩΝ ΤΗΣ LDH ΤΟΥ ΠΡΟΣΤΑΤΙΚΟΥ ΥΓΡΟΥ ΣΤΗ ΔΙΑΓΝΩΣΗ ΤΗΣ ΧΡΟΝΙΑΣ ΠΡΟΣΤΑΤΙΤΙΔΑΣ

By ΝΙΚΟΛΑΟΣ ΣΤΑΥΡΟΠΟΥΛΟΣ

Abstract

PROSTATITIS APPEARS TO BE ONE OF THE MOST COMMON INFLAMMATORY ENTITIES ENCOUNTERED IN UROLOGIC PRACTICE. HOWEVER IT IS GENERALLY AGREED THAT THIS DISORDER QUITE OFTEN PRESENTS DIAGNOSTIC DIFFICULTIES DUE TO THE LACK OF PRECISE DIAGNOSTIC CRITERIA. THE MAIN IDEA OF THIS STUDY WAS TO USE THE RATIO OF LDH5/LDH1 IN THE PROSTATIC FLUID AS A DIAGNOSTIC PARAMETER OF EITHER INFECTION OR INFLAMMATION OF THE PROSTATE GLAND. FOR THIS PURPOSE 54 PATIENTS WITH SYMPTOMS OF CHRONIC PROSTATITIS WERE EVALUATED. DIAGNOSES WERE BASED ON HISTORY, PHYSICAL EXAMINATION, AND URINE AND PROSTATIC FLUID MICROSCOPIC EXAMINATION AND CULTURES. AT THE SAME TIME THE RATIO OF LDH5/LDH1 WAS DETERMINED BY AGAR GEL ELECTROPHORESIS OF THE PROSTATIC FLUID. TEN OTHER NORMAL SUBJECTS WERE ALSO STUDIED BYTHE SAME MEANS AND SERVED AS CONTROLS. FROM THIS STUDY THE FOLLOWING CONCLUSIONS CAN BE DRAWN: 1. THE DIAGNOSIS OF CHRONIC PROSTATITIS IS IN MANY CASES UNCERTAIN WHEN BASED ONLY ON MICROSCOPIC EXAMINATION AND CULTURE FINDINGS OF THEPROSTATIC FLUID. ON THE OTHER HAND THE DIFFERENTIAL DIAGNOSIS BETWEEN PROSTATIC INFLAMMATION AND PROSTATODYNIA BASED ON THE SAME CRITERIA IS NOT INFREQUENTLY IMPOSSIBLE. 2. THE RATIO LDH5/LDH1 IS ELEVATED IN PATIENTS WITH EITHER PROSTATIC INFECTION OR PROSTATIC INFLAMMATION. IN THIS STUDY THE MEAN LDH5/LDH1RATIO FOR PATIENTS WITH NON BACTERIAL AND BACTERIAL PROSTATITIS DIFFERED SIGNIFICANTLY FROM THE RATIO IN THE NORMAL CONTROLS (ABSTRACT TRUNCATED)

Publisher: National and Kapodistrian University of Athens
Year: 1984
DOI identifier: 10.12681/eadd/8243
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