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Rheumatology Reports 2013; volume 5:e2Muscular metastasis heraldingmedullary carcinoma of thethyroid



Medullary thyroid carcinoma (MTC) com-monly metastasizes locally to the cervical lymph nodes and distantly to the liver, lungs and bones. Metastatic involvement of the mus-cles is extremely rare. We reported an unusual case of undiagnosed MTC presenting with symptoms related to metastatic lesions of the brachoradialis and the gluteus medius mus-cles. A 53-year-old man consulted for a painful mass of the right forearm and atrophy of the quadriceps. Ultrasonography revealed a het-erogeneous collection in the forearm. Computed tomographic scan showed a mass in the right lung, an enlargement of mediastinal lymph nodes and solid masses in the right glu-teus medius and the left iliopoas muscle extending to the left iliac bone. Pulmonary biopsies displayed findings consistent with metastatic MTC. Fine needle aspiration cytol-ogy from the right arm swelling revealed a lesion with the same calcitonin immunostain-ing patterns as the lung metastasis. The diag-nosis of multiple metastases (lung, muscle and bone) of MTC is established. The patient has received local radiation therapy and was planned for chemotherapy. Muscular metas-tases from MTC are rare and although their prognosis is poor, local treatment may be worthwhile

Year: 2016
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