on glutamatergic memory processes olytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland on changes in gene and protein expression in response to glucocorticoids [13–16]. Because genomic mechanisms take some time to develop, such a mechanism cannot apply to extremely rapid effects of glucocorticoids reported for some cognitive operations (for example, learning and re-trieval when tests are given shortly after the enhancement of glucocorticoid levels). Importantly, recent work has underscored the potential of glucocorticoids to affect mem-ory processes and synaptic plasticity by interacting with glutamatergic mechanisms (Box 3) through both nonge-nomic and genomic pathways. The first part of this article discusses studies tha

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