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Estimation of reference values for dioxin, furan, and PCB congener concentrations for the Australian population

By Lesa Aylward, Leisa-Maree Toms and Jochen Mueller


Population-representative data for dioxin and PCB congener concentrations are available for the Australian population based on measurements in age- and gender-specific serum pools.1 Such data provide a basis for characterizing the mean concentrations of these compounds in the population, but do not provide information on the inter-individual variation in serum concentrations that may exist in the population within an age- and gender-specific group. Such variation may occur due to inter-individual differences in long-term exposure levels or elimination rates. Reference values are estimates of upper percentiles (often the 95th percentile) of measured values in a defined population that can be used to evaluate data from individuals in the population in order to identify concentrations that are elevated, for example, from occupational exposures.2 The objective of this analysis is to estimate reference values corresponding to the 95th percentile (RV95s) for Australia on an age-specific basis for individual dioxin-like congeners based on measurements in serum pools from Toms and Mueller (2010)

Topics: 050206 Environmental Monitoring, dioxin, furan, Australian population, reference values
Publisher: International Advisory Board and
Year: 2012
OAI identifier:

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  1. (2010). Chemical Monitoring Initiative: Australian human blood sample collection and chemical testing. FINAL REPORT. A consultancy funded by the Australian Government Department of the Environment, Water, Heritage and the Arts.
  2. National Health and Nutrition Examination Survey (NHANES) 2003-2004 data. Available at:

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