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Relation of Serum Oxygen Radical Absorbance Capacity with Metabolic Risk Factors in Human Volunteers

By Ho Kyung Kwak and Sun Yoon


Oxygen radical absorbance capacity(ORAC) is known to be a sensitive and simple method to determine total antio-xidant capacity(TAC) in biological samples. While TAC has received great attention with its relation to pathogenesis in the progression of several diseases, little is known about association of ORAC with metabolic risk factors. The aim of this study is to evaluate the relationship between ORAC and serum lipid profiles, fasting glucose and anthropometric measures. One hundred seventeen volunteers participated in the study. Perchloric acid treated serum was used to de-termine ORACpca. Mean ORACpca of subjects whose serum total cholesterol(TC) concentrations were ≥ 200 mg/dl was significantly(P < 0.05) higher than that of subjects whose TC concentrations were < 200mg/dl. There were significantly positive correlations between ORACpca and serum concentrations of TC(P < 0.05) and low density lipoprotein (LDL) cholesterol(P < 0.01). The positive relation between cholesterol concentrations and ORACpca in serum may suggest an elevated TAC against oxidative stress associated with the cardiovascular risk factors. (J Community Nutrition 7(4) : 215

Topics: KEY WORDS, oxygen radical absorbance capacity·cholesterol·triglyceride·body mass index·human
Year: 2016
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