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Preparation of porous calcium phosphate ceramic scaffold in bone tissue engineering

By Wei Zheng, Cheng Yan, Feng Lin, Wei Fan, Clayton J. Adam and Adekunle Oloyede


Calcium Phosphate ceramic has been widely used in bone tissue engineering due to its excellent biocompatibility and biodegradability. However, low mechanical properties and biodegradability limit their potential applications. In this project, hydroxyapatite (HA) and calcium phosphate bioglass were used to produce porous tri-calcium phosphate (TCP) bio-ceramic scaffolds. It was found that porous TCP bioceramic could be obtained when 20wt percent bioglass addition and sintered in 1400 degrees celsius for 3 h. Significantly higher compressive strength (9.98 MPa) was achieved in the scaffolds as compared to those produced from tCP power (<3 MPa). The biocompatibility of the scaffold was also estimated

Topics: 090301 Biomaterials, 091201 Ceramics, Tissue Engineering, Bone, Scaffold, Mechanical Property, Tri-Calcium Phosphate, Hydroxyapatite, Bioactive Glass
Publisher: IEEE
Year: 2010
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