Abstract

mitter release is more affected than spon-taneous release by the absence of VAMP2 is consistent with the idea that the SNARE complex is already at least partially assem-bled and awaits the arrival of the calcium trigger to facilitate full assembly and the completion of membrane fusion (12, 13). In contrast, spontaneous release (minis) and sucrose-evoked release, reflecting non – (or low–) calcium-dependent fusion events, are less severely affected by the loss of SNARE catalysis. Notably, 90 % of this fusion was eliminated in the absence of VAMP2, indicating that the preferred mechanism of fusion does actually depen

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oai:CiteSeerX.psu:10.1.1.913.2608Last time updated on 11/1/2017

This paper was published in CiteSeerX.

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