Skip to main content
Article thumbnail
Location of Repository

The drugulator - a new method for performing dosage calculations\ud

By Ronald Monson


In this paper we introduce The Drugulator - a new method for performing dosage calculations at the administration stage of a patient's medical management. In this method users first construct a dosage's mathematical formulation from within the Drugulator's structured interface. This formulation is then evaluated by sending it to an attached computational backend that then returns any constituent calculations along with the patient's final dose. This process of Formulaic and Computationally-Aided Dosing (FCAD), and in particular, the single-interface Drugulator implementation described here, makes it practical to readily automate a wide range of dosage calculations at the point of care. This practicality also enables further automation through a progressive integration with existing medical systems. Finally, we argue that the principle underpinning the deployment of a single interface can also be used to improve the usability of those computer provider order entry systems that include clinical decision support (CPOEcds)

Topics: 230000 Mathematical Sciences, 320000 Medical and Health Sciences, School of Engineering and Science, drug dosage calculations, medication errors, educational technology, algorithms, automation, systems integration
Publisher: Health Informatics Society of Australia (H I S A) Ltd
Year: 2009
OAI identifier:

Suggested articles


  1. (2004). A conceptual framework for evaluating outpatient electronic prescribing systems based on their functional capabilities.
  2. (2006). A pragmatic approach to implementing best practices for clinical decision support systems in computerized provider order entry systems.
  3. (2007). A roadmap for national action on clinical decision support.
  4. (2007). Administration of drugs in Publication Number.
  5. (2001). Adverse events in British hospitals: Preliminary retrospective record review.
  6. (1988). Automated infusion system with dose rate calculator.
  7. (2005). Clinical decision support and electronic prescribing systems: A time for responsible thought and action.
  8. (2007). Clinical Information Technology. Electronic prescribing systems in pediatrics: The rationale and functionality requirements. Pediatrics.
  9. (2003). Computer physician order entry: Benefits, costs, and issues. Annals of Internal Medicine.
  10. Computer system for determining a drug dosage. 2005; World Intellectual Property Organization WO/2005/041105. Correspondence Dr.
  11. (2007). Cpoe: Sufficient, but not perfect, evidence for taking action.
  12. (2005). Detection and prevention of medication errors using real-time bedside nurse charting.
  13. (2006). Development and testing of a scale to assess physician attitudes about handheld computers with decision support.
  14. Drip blender, mixing tube, liquid drug container, liquid mixture container, drip blending system and method of blending drip. 2004; World Intellectual Property Organization WO/2004/045489.
  15. (1995). Drug-related morbidity and mortality. A cost-of-illness model.
  16. (2005). Effect of cpoe user interface design on user-initiated access to educational and patient information during clinical care.
  17. (1992). Electronic fluid flow rate controller for controlling the infusion of intravenous drugs into a patient.
  18. (1995). et a. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE prevention study group.
  19. (1995). et a. Systems analysis of adverse drug events. ADE prevention study group.
  20. (2002). Evaluating the capability of information technology to prevent adverse drug events: A computer simulation approach.
  21. (1997). Factors related to errors in medication prescribing.
  22. (2002). Frequency and determinants of drug administration errors in the intensive care unit. Critical Care Medicine.
  23. (1997). Hand held apparatus for performing medical calculations.
  24. (2000). Handheld medical calculator and medical reference device.
  25. (2005). High rates of adverse drug events in a highly computerized hospital. Archives of Internal Medicine.
  26. (2005). Implementing a commercial rule base as a medication order safety net.
  27. (2003). Improving patient safety across a large integrated health care delivery system. International Journal for Quality in Health Care.
  28. (2003). Incidence and preventability of adverse drug events among older persons in the ambulatory setting.
  29. (1998). Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies.
  30. (2005). Information retrieval performance of probabilistically generated, problem-specific computerized provider order entry picklists: A pilot study.
  31. (2002). Intensive care calculator : Medication dose calculator.
  32. (2006). Interface terminologies: Facilitating direct entry of clinical data into electronic health record systems.
  33. (2001). Medication errors and adverse drug events in pediatric inpatients.
  34. (2004). Medication errors involving continuously infused medications in a surgical intensive care unit. Critical Care Medicine.
  35. (2006). Medication-related clinical decision support in computerized provider order entry systems: A review.
  36. (2003). Neural network drug dosage estimation.
  37. (2007). Nurses relate the contributing factors involved in medication errors.
  38. Nursing calculators.
  39. (2004). Organization and representation of patient safety data: Current status and issues around generalizability and scalability.
  40. (2001). Physician satisfaction with two order entry systems.
  41. (2003). Preparation and use of preconstructed orders, order sets, and order menus in a computerized provider order entry system.
  42. (1976). Preventability of adverse drug reactions [letter]. Annals of Internal Medicine.
  43. (1998). Providing patient-specific drug information.
  44. (1997). Recommendations for responsible monitoring and regulation of clinical software systems.
  45. (2003). Ten commandments for effective clinical decision support: Making the practice of evidence-based medicine a reality.
  46. (1997). The costs of adverse drug events in hospitalized patients. Adverse drug events prevention study group.
  47. The development and evaluation of an integrated electronic prescribing and drug management system for primary care.
  48. (2004). The epidemiology of prescribing errors: The potential impact of computerized prescriber order entry. Archives of Internal Medicine.
  49. (1991). The nature of adverse events in hospitalized patients. Results of the Harvard medical practice study ii. New England Journal of Medicine.
  50. (2007). The version referred to in this paper has been frozen and is accessible from
  51. This involves a potential partnership between Comet (http:// and Grey Innovations (
  52. (1999). Tutorial device and method for determining drug dosages.
  53. (2000). Using information technology to reduce rates of medication errors in hospitals.
  54. (2007). Viewpoint: Controversies surrounding use of order sets for clinical decision support in computerized provider order entry.
  55. (2006). Why did that happen? Exploring the proliferation of barely usable software in healthcare systems.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.