Model-based Monitoring of Septic Shock Treated with Large-pore Hemofiltration Therapy

Abstract

Abstract: The diagnostic ability of model-based monitoring systems offer significant clinical potential. This research tests, the clinical ability of a model-based system for tracking hemodynamic changes in a porcine study on septic shock and large pore hemofiltration (LPHF) therapy. Typically available or inferable intensive care unit (ICU) measurements are used to identify subject-specific models of the cardiovascular system (CVS). The approach accurately identified known trends of septic shock including a drop in systemic vascular resistance and right ventricular distension, and accurately predicted left and right ventricular volumes and pressures. The method also quantified each subject’s individual response to the disease and corresponding LPHF therapy. These results indicate the clinical potential of using model-based methods for tracking acute hemodynamic changes in cardiovascular compromised individuals

Similar works

Full text

thumbnail-image
oai:CiteSeerX.psu:10.1.1.899.2443Last time updated on 11/1/2017

This paper was published in CiteSeerX.

Having an issue?

Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.