Skip to main content
Article thumbnail
Location of Repository

Synthesis of Two Novel Boronic Acid Probes for the Molecular Recognition of Saccharides

By Christopher W. Tudbman


Normally the detection of biologically important molecules such as saccharides is difficult. Few chemical sensing mechanisms have been developed for saccharides as they are uncharged, neither fluoresce nor quench fluorescence, and are normally present in aqueous media, which presents competitive hydrogen bonding. The recognition and measurement of saccharides has been achieved recently by certain synthetic molecular receptors or \u22probes,\u22 containing a boronic acid receptor moiety, which circumnavigates the normal difficulties associated with the detection of saccharides. The synthesis of two novel bidentate boronic acid molecular probes was attempted with the intent of testing their relative binding selectivity in the molecular recognition of simple monosaccharides such as glucose, fructose,and galactose

Topics: Saccharides
Publisher: ScholarWorks@GVSU
Year: 1999
OAI identifier:
Provided by: Scholarworks@GVSU

Suggested articles

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.