Skip to main content
Article thumbnail
Location of Repository

Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants

By E. East, K. Murphy and J. Phillips

Abstract

Tissue engineered culture models provide a powerful tool for neuroscience research1. They overcome limitations associated with monolayer cultures of neurons and glia by maintaining cells in a more realistic 3D spatial arrangement, and permit continuous monitoring and control of variables that cannot be achieved in animal models. Here we report the development of a system for recording electrophysiological behaviour in neurons in 3D culture

Year: 2011
OAI identifier: oai:oro.open.ac.uk:29160
Provided by: Open Research Online

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.