ANALYTIC REVIEWS Hyperbaric Oxygen Therapy


The physiological effects of hyperbaric oxygen extend beyond the elevation of oxygen concentration in body tissues, and clinical data is available to support its use in more than gas bubble diseases. Hyperbaric medicine is discussed within the context of its recognized mecha-nisms of action. The experimental data and clinical ex-perience for hyperbaric oxygen therapy are reviewed for the following conditions: clostridial myonecrosis, necrotizing soft-tissue infections, chronic refractory os-teomyelitis, radiation necrosis, refractory cutaneous ul-cerations, compromised skin grafts and flaps, crush in-jury and acute peripheral ischemia, carbon monoxide poisoning, arterial gas embolism, decompression sick-ness, and thermal burns. Risks associated with hyper-baric oxygen therapy are discussed, and cost analysis data are noted for specific conditions

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