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Running title: EGCG induces oxidative stress and DNA damage in vivo and in vitro. Key words: EGCG · oxidative stress · DNA damage · γ-H2AX · 8-OHdG · cancer prevention Abbreviations: EGCG, (-)-epigallocatechin-3-gallate; DSB, double-strand break; γ-H2AX, phosphorylated histone 2A variant X; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; NAC, N

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