Article thumbnail

Letters to the Editor

By Micronutrient Concentrations


atherosclerosis in adults with HIV Dear Sir: Falcone et al (1) examined serum micronutrient concentrations along with surrogate markers of atherosclerosis in a cohort of HIV-infected adults. They reported that ‘‘the highest tertile of serum vitamin E concentration was associated with higher common and internal carotid intima-media thickness (c-IMT) and coronary artery calcium (CAC) scores (P, 0.05 for c-IMT and CAC)’ ’ (p 1213). They concluded that ‘‘elevated serum vitamin E concentrations... may increase the risk of cardiovascular complications in HIV-infected adults’ ’ (p 1213). However, we believe that the authors ’ conclusion that vitamin E is adversely affecting atherosclerosis is not convincing, is based solely on associations that cannot establish causation, and has no mechanistic basis. Furthermore, on the basis of current descrip-tions of adverse consequences of highly active antiretroviral therap

Year: 2016
OAI identifier: oai:CiteSeerX.psu:
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • (external link)
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.