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EDITORIAL Genes and cardiovascular risk

By Ole Faergeman

Abstract

This editorial refers to ‘Influence of common genetic vari-ation on blood lipid levels, cardiovascular risk, and coron-ary events in two British prospective cohort studies’, by S. Shah et al., doi:10.1093/eurheartj/ehs243 and ‘Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protec-tion Study’, by J.C. Hopewell et al., doi:10.1093/eur-heartj/ehs344 If DNA really is the ‘blueprint ’ for life, how can genetic analysis fail to tell us what life has in store for us? One of two excellent articles in this journal shows us that the usual way to calculate risk of cardiovascular disease, such as ascertaining smoking habits and measuring blood pressure and cholesterol, is better than analyses for commonly occurring variations in DNA sequences. From the other article, we learn that a statin drug reduces risk of cardiovas

Year: 2016
DOI identifier: 10.1093/eurheartj
OAI identifier: oai:CiteSeerX.psu:10.1.1.817.3830
Provided by: CiteSeerX
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