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By Sritama Nath, Lopamudra Das Roy and Pinku Mukh


MUC1high PDA patients also express high levels of cyclooxygenase 2 (COX-2) and show poor prognosis. The cytoplasmic tail of MUC1 (MUC1-CT) partakes in oncogenic signaling, resulting in accelerated can-Human PDA cell lines Hs766T, Capan-2, HPAFII, HPAC and CFPAC, BxPC3, Capan-1, and MIA-PaCa-2 were obtained from ORIGINAL ARTICLEopen-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND),PDA.Muc1KO and PDA.MUC1 as described by Besmer et al16 are used. KCM and KCKO cell lines were generated from PDA.MUC1 and PDA.Muc1 KO mice, respectively.16 appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (

Year: 2016
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