Experimental

Abstract

disorder in main residue; R factor = 0.052; wR factor = 0.140; data-to-parameter ratio = 9.6. In the title compound, C12H11FN4O2, the pyridine ring is connected to a benzene ring by a –CH2—NH2- chain. The nitro group is twisted out of the pyridine ring plane [torsion angle O—N—C—C = 10.41 (10)]. An intramolecular N— H O hydrogen bond occurs. The fluorobenzene ring is disordered over two positions [occupancy ratio = 0.59 (3):0.41 (3)]. Intermolecular N—H O and N—H N hydrogen bonds stabilize the crystal structure. Related literature The title compound is an intermediate in the synthesis of analgesic drugs. For the analgesic properties of flupirtine (systematic name ethyl{2-amino-6-[(4-fluorobenzyl)amino]

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oai:CiteSeerX.psu:10.1.1.769.3007Last time updated on 10/30/2017

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