Article thumbnail

Communityassociated MRSA (CA-MRSA): an emerging pathogen in infective endocarditis

By B. Cherie Millar, Bernard D. Prendergast and John E. Moore

Abstract

Over the last decade, a novel methicillin-resistant Staphylococcus aureus (MRSA) has emerged, primarily associated with healthy individuals within the community. This organism is distinct from healthcare-associated MRSA (HA-MRSA) in terms of epidemiology, microbiology and clinical manifes-tation and as such has been defined as community-associated MRSA (CA-MRSA). Given that S. aureus is a major aetiological agent of infective endocarditis (IE), particularly associated with the iv drug user population, reports of IE attributed to CA-MRSA are now emerging in the literature. The aims of this article are to (i) define and contrast CA-MRSA with HA-MRSA; (ii) review the published cases of CA-MRSA IE to date; and (iii) evaluate the current international recommendations for antibiotic prophylaxis and treatment regimens for IE in relation to CA-MRSA

Topics: community-acquired MRSA, PVL, Panton-Valentine leucocidin
Year: 2008
OAI identifier: oai:CiteSeerX.psu:10.1.1.541.9648
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://jac.oxfordjournals.org/... (external link)
  • http://jac.oxfordjournals.org/... (external link)
  • http://citeseerx.ist.psu.edu/v... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.