Self-interacting mass-dimension one fields for any spin

According to Ahluwalia and Grumiller, massive spin-half fields of mass-dimension one can be constructed using the eigenspinors of the charge-conjugation operator (Elko) as expansion coefficients. In this paper, we generalize their result by constructing quantum fields from higher-spin Elko. The kinematics of these fields are thoroughly investigated. Starting with the field operators, their propagators and Hamiltonians are derived. These fields satisfy the higher-spin generalization of the Klein-Gordon but not the Dirac equation. Independent of the spin, they are all of mass-dimension one and are thus endowed with renormalizable self-interactions. These fields violate Lorentz symmetry. The violation can be characterized by a non-Lorentz-covariant term that appears in the Elko spin-sums. This term provides a decomposition of the generalized higher-spin Dirac operator in the momentum space thus suggesting a possible connection between the mass-dimension one fields and the Lorentz-invariant fields3011CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ313285/2013-

National Education Plan and teaching quality: considerations on the self-efficacy of the school agents

Este texto é uma reflexão motivada pela aprovação do Plano Nacional de Educação (PNE) e pela expectativa que ele traz como instrumento legal e metodológico para a melhoria da educação nacional. O objetivo foi questionar se o PNE contém os elementos que conduzem à melhoria da educação e se o faz em termos que independem dos executores para definir suas ações. São apresentadas e discutidas as metas e as estratégias do PNE que têm a melhoria do ensino como objeto. Em face da generalidade e do foco daquelas, concluímos que serão necessárias novas leituras sobre elas nos planos estaduais e municipais. Focalizamos a discussão na questão da saúde dos docentes, que aparece na estratégia 7.31, e sobre seu enfrentamento com o auxílio do constructo de autoeficácia.39167183Reflection motivated by the approval of the National Education Plan (PNE) and the expectation that it brings as legal and methodological tool for the improvement of national education. The objective is to question whether the PNE contains the elements that lead to better education and does so in terms that are independent of agents to define their actions. The goals and strategies of the PNE, that have better education as an objective, are presented and discussed. Given the generality and the focus of those, it is concluded that will require new readings about them will be required in state and municipal plans. The discussion is focused on the issue of teachers health, which is shown in strategy 7.31, and on its confrontation with the aid of the construction of self-efficacy

Analysis of the oral manifestations of breast cancer patients who performed with imunobiological treatment through a systematic literature review

Orientador: Jacks Jorge JuniorDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências MédicasResumo: O câncer de mama é uma das doenças mais comuns nas mulheres em todo o mundo. Representa 25% de todos os cânceres, com uma estimativa de que em 2020 se diagnostiquem mais de 66 mil casos, no Brasil. Segundo o INCA, o câncer de mama corresponde a 29% dos novos casos de cânceres, no país. Entre as alternativas de tratamentos para esta doença se encontram os imunoterápicos (anticorpos monoclonais), que são utilizados como terapia adjuvante, no tratamento de alguns subtipos dessa doença, com a finalidade de prevenir e reduzir a incidência de metástases ósseas e os riscos de fraturas do esqueleto. Entretanto, estes medicamentos podem apresentar efeitos adversos, quando são empregados dentro de um regime antineoplásico e associados a outra classe de antireabsortivos como os bifosfonatos, por exemplo. Dessa forma, este trabalho realizou uma revisão sistemática de artigos publicados nas bases de dados Pubmed e Scopus entre os anos de 2009 e 2019, com o objetivo principal de responder se o uso de anticorpos monoclonais (imunobiológicos), no tratamento de pacientes com câncer de mama gera alterações orais. A partir deste estudo podemos concluir que os imunobiólogicos causam reações na cavidade oral dos pacientes. Contudo, essas reações não ocorrem de forma isolada, mais associada a outros medicamentos antirreabsortivos e ao regime antineoplásico, ao qual o paciente é submetido. Os imunobiológicos geram alterações típicas na mucosa bucal e dermatológicas pouco exploradas na literatura. Nessas condições, a avaliação odontológica prévia da cavidade oral do paciente é essencial para evitar complicações clínicas durante o tratamento oncológicoAbstract: Breast cancer is one of the most common diseases in women worldwide. It represents 25% of all cancers, with an estimate that in 2020 more than 66 thousand cases will be diagnosed in Brazil. According to INCA, breast cancer corresponds to 29% of new cancer cases in the country. Among the alternative treatments for this disease are immunotherapeutic agents (monoclonal antibodies), which are used as adjuvant therapy in the treatment of some types of breast cancer, in order to prevent and reduce the incidence of bone metastases and the risks of skeletal fractures. However, these drugs can have adverse effects when they are used within an antineoplasic regimen and associated with another class of anti-resorptives such as bisphosphonates, for example. This study carried out a systematic review of articles published in the Pubmed and Scopus databases between the years 2009 and 2019, with the main objective of answering whether the use of monoclonal antibodies (immunotherapy) in the treatment of patients with breast cancer generates changes oral. From this study we can conclude that immunobiologists cause reactions in patients' oral cavities. However, these reactions do not occur in isolation, more associated with other antiresorptive drugs and the antineoplastic regimen, to which the patient is submitted. Immunotherapy generate typical changes in the oral mucosa and dermatological scarcely explored in the literature. Under these conditions, dental evaluation of the oral cavity prior to and during patient treatment is essential to avoid clinical complications during cancer treatmentMestradoOncologiaMestra em Ciência

Prevalence of Burnout syndrome in health professionals of an onco-hematological pediatric hospital

Identificar a prevalência da Síndrome de Burnout em profissionais médicos, enfermeiros e técnicos de enfermagem que trabalham em um hospital oncohematológico infantil no estado de São Paulo. Estudo exploratório, descritivo, com delineamento transversal e abordagem quantitativa, cuja amostra foi composta 188 profissionais de saúde. Os dados foram coletados utilizando-se dois instrumentos de autopreenchimento: o Maslach Burnout Inventory (MBI-HSS) e um formulário de dados biossociais, além de um roteiro de observação não participante. Apresentaram alta despersonalização 29,8% dos enfermeiros e baixa realização profissional 27,8% dos médicos e 25,5% dos técnicos de enfermagem. Foram identificados com altos escores em pelo menos dois domínios do Burnout 19,2% de enfermeiros, 16,8% dos técnicos de enfermagem e 16,6% dos médicos. Existe importante vulnerabilidade dos profissionais de saúde para a Síndrome de Burnout, potencializada pela identificação da presença elevada de cada uma de suas dimensões no ambiente de trabalho hospitalar.492251258To identify the prevalence of Burnout Syndrome in medical professionals, nurses and nursing technicians working in an Onco-Hematological Pediatric Hospital in São Paulo. An exploratory, descriptive study with cross-sectional design and quantitative approach, with a sample of 188 health professionals. Data were collected using two self-report instruments: the Maslach Burnout Inventory (MBI-HSS) which is a biosocial data form, and a non-participant observation guide. High depersonalization for nurses (29.8%), low job performance for physicians (27.8%), and of nursing technicians (25.5%). High scores were identified in at least two domains of Burnout in 19.2% of nurses, 16.8% of nursing technicians, and 16.6% of doctors. Health professionals are highly vulnerable to each of the dimensions of Burnout syndrome - namely emotional exhaustion, alienation, and low job performance/satisfaction- in the hospital work. || Identificar la prevalencia del Síndrome de Burnout en profesionales médicos, enfermeros y técnicos de enfermería que trabajan en un hospital oncohematológico infantil en el Estado de São Paulo. Estudio exploratorio, descriptivo, de corte transversal y abordaje cuantitativo, cuya muestra estuvo compuesta de 188 profesionales de salud. Los datos fueron recogidos utilizándose dos instrumentos de autorelleno: el Maslach Burnout Inventory (MBI-HSS) y un formulario de datos biosociales, además de un guión de observación no participante. Presentaron alta despersonalización el 29,8% de los enfermeros y baja realización profesional el 27,8% de los médicos y el 25,5% de los técnicos de enfermería. Fueron identificados con altos puntajes en por lo menos dos dominios del Burnout el 19,2% de los enfermeros, el 16,8% de los técnicos de enfermería y el 16,6% de los médicos. Existe una importante vulnerabilidad de los profesionales de salud para el Síndrome de Burnout, potenciada por la identificación de la presencia elevada de cada una de sus dimensiones en el ambiente de trabajo hospitalario

Apresentação: Convivialidade em sociedades desiguais: uma proposta para colaboração interdisciplinar

Conviviality emerged in the 1970s as a theoretical and practical programme with the book Tools for Conviviality, by Ivan Illich(1973). From the 2000s on its use has spread throughout various disciplines and themes, resulting in a quite polysemic understan38191

Metabolic and structural bone disturbances induced by hyperlipidic diet in mice treated with simvastatin

Simvastatin can modulate lipid and bone metabolism. However, information related to the interaction between diet and simvastatin on bone structure and biomechanics is scarce. Thus, this study evaluated the effects of simvastatin on femoral biomechanics and cortical/trabecular bone structure in wild‐type mice nourished with a hyperlipidic diet. Three‐month‐old male wild‐type mice (C57BL6 strain) were divided into four groups: (1) group W, nourished with a standard diet; (2) group WH, fed a hyperlipidic diet; (3) group WS, nourished with a standard diet plus oral simvastatin (20 mg/kg/day); and (4) group WHS, fed a hyperlipidic diet plus oral simvastatin (20 mg/kg/day). All animals received only their specific diet and water for 60 days. Blood samples were collected for the analysis of calcium, triglycerides, total cholesterol (TC) and fraction serum levels. Diet manipulation was able to induce a dyslipidaemic status in mice, characterized by triglyceride and TC rise in WH animals. Simvastatin prevented hypercholesterolaemia and reduced TC and LDL serum levels, but did not prevent hypertriglyceridaemia and HDL serum levels in the WHS group. In the WH mice the hyperlipidaemia was associated with reduction in trabecular bone thickness, femur structural and material property alterations. Simvastatin prevented these morphological alterations and minimized femur biomechanical changes in WHS mice. Taken together, the results indicated that the hyperlipidic diet intake acts as a risk factor for bone integrity, generating bones with reduced resistance and more susceptible to fractures, an effect attenuated by simvastatin that is potentially related to the modulatory action of this drug on lipid and bone metabolism.96426126

The Brazilian postal system in transformation: proposals and changes in market regulation and restructuring of the organizational model of the Brazilian Post and Telegraph Company (1994-2011)

Objetiva-se neste artigo responder a seguinte questão: quais foram as propostas e as mudanças nos mecanismos de regulação do mercado postal brasileiro e na estrutura organizacional da Empresa Brasileira de Correios e Telégrafos (ECT) entre 1994 e 2011? Verifica-se que, entre 1994 e 2002, a proposta do governo federal, apresentada em 1999 por meio da "Nova Lei postal", previa a criação do Sistema Nacional de Correios, liberalizando o mercado postal, criando um órgão regulador e transformando a ECT em uma empresa de economia mista. Apesar da não aprovação do projeto de lei, algumas de suas propostas foram retomadas, a partir de 2008, pelos diagnósticos e propostas do governo Lula para reestruturar o setor postal brasileiro. As propostas subsidiaram a aprovação da Lei nº 12.490 de 2011, que internacionalizou a ECT, ampliou os segmentos de mercado da empresa e a reestruturou com base no modelo das sociedades anônimas48613551380sem informaçã

O intelectual feiticeiro : Edison Carneiro e o campo de estudos das relações raciais no Brasil

sem informaçãosem infomação303343348sem informaçãosem informaçãosem informaçã

Plato. Hippias Major

sem informaçãoTrata-se de tradução do Hípias Maior de Platão para o Português, com algumas notas de elucidação e justificação das opções.26sem informaçãosem informaçãosem informaçã

The effect of milrinone on splanchnic and cerebral perfusion in infants with congenital heart disease prior to surgery

Despite the advancement in the postoperative care of neonates with congenital heart disease (CHD), there is little information on preoperative management of systemic and regional hemodynamics, which may be related to outcomes. We aimed to determine the preoperative effect of milrinone, a phosphodiesterase III inhibitor, on cardiac output and splanchnic and cerebral perfusion in neonates with CHD. Neonates with CHD requiring cardiac surgery were enrolled in a prospective, single-blinded study once a clinical decision of starting milrinone (0.75 μg/kg per minute intravenously) using institutional criteria was made. Demographic and clinical variables and outcomes were recorded. Combined cardiac output and measures of splanchnic (superior mesenteric and celiac arteries) and cerebral (anterior and middle cerebral arteries) perfusion were determined by Doppler studies at 0, 6, 24, and 48 h after milrinone infusion. Investigators were unaware of intervention time points and patients in analyzing blood flow measurements. Seventeen term (39.2 ± 1.3 weeks) neonates were included with hypoplastic left-sided heart syndrome (78.5%) as the most common diagnosis. Combined cardiac output increased by 28% within 48 h (613 ± 154 vs. 479 ± 147 mL/kg per minute at baseline, P < 0.05). Superior mesenteric artery mean velocity increased at 6 h and throughout 48 h of milrinone infusion (P < 0.05). Peak and mean velocities at cerebral arteries increased with milrinone infusion (P < 0.05∼0.08), and the corresponding changes at celiac artery were modest. There were no significant changes in splanchnic and cerebral resistive and pulsatility indices during milrinone infusion. Milrinone increases cardiac output with concurrent effects on splanchnic and cerebral blood flows during the short-term preoperative use in neonates with CHD.44211512