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    Stability, deactivation and regeneration study of a newly developed HZSM-5 and Ni-doped HZSM-5 zeolite catalysts for ethanol-to-hydrocarbon conversion

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    This work investigates the stability and regeneration of HZSM-5 and Ni/HZSM-5 catalysts in the ethanol-to-hydrocarbon conversion. The catalysts were characterised using different techniques and evaluated at 623 K and 7 h−1 for 96 h TOS with two regeneration cycles. HZSM-5 showed high stability with 100% ethanol conversion, while Ni/HZSM-5 catalysts maintained 100% stability for 48 h before dropping. Regenerated catalysts were comparable to the originals in terms of product distribution, stability, and performance. HZSM-5 preferred BTX, while Ni-doped catalysts favoured C5-C8, C9-C12, and C12+ synthesis. The regeneration process restored catalytic activity, especially for the Ni-doped catalysts, extending their life and reducing replacement costs

    Effect of hydro-alcoholic extract of Nigella sativa on cisplatin-induced memory impairment and brain oxidative stress status in male rats

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    Objective: Studies have shown the complications of chemotherapy on learning and memory. Empirical evidence suggests that Nigella sativa (NS) has neuroprotective activities. Therefore, the aim of our study was to investigate the effects of NS on cisplatin-induced memory impairment.Materials and Methods: This study was conducted on 40 male rats grouped as: control (saline: 2 ml/kg, intraperitoneally (IP), once weekly/2 weeks), cisplatin (Cis, 2 mg/kg, IP, once weekly/2 weeks), NS (200 mg/kg, IP, once weekly/2 weeks), Cis +NS 200 (2 mg/kg Cis + 200 mg/kg NS, IP, once weekly/2 weeks), and Cis +NS 400 (2 mg/kg Cis + 400 mg/kg NS, IP, once weekly/2 weeks). Morris water maze (MWM) test was used to assess spatial learning and memory. In addition, superoxide dismutase (SOD) activity, and thiol and malondialdehyde (MDA) levels were evaluated in the brain.Results: Cis significantly enhanced the traveled distance and time spent in the target quadrant in the MWM test. Additionally, MDA levels increased in the Cis group, while thiol and SOD decreased in this group. As a result of treatment with NS, behavioral results were reversed in the groups receiving NS compared to the Cis group. Also, NS reduced MDA level but improved SOD and thiol levels in brain tissue samples.Conclusion: NS could improve memory impairment and oxidative stress in animals receiving Cis. Therefore, NS could be used as a potential food supplement to prevent neurotoxicity in patients undergoing chemotherapy

    Robotont 3–an accessible 3D-printable ROS-supported open-source mobile robot for education and research

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    Educational robots offer a platform for training aspiring engineers and building trust in technology that is envisioned to shape how we work and live. In education, accessibility and modularity are significant in the choice of such a technological platform. In order to foster continuous development of the robots as well as to improve student engagement in the design and fabrication process, safe production methods with low accessibility barriers should be chosen. In this paper, we present Robotont 3, an open-source mobile robot that leverages Fused Deposition Modeling (FDM) 3D-printing for manufacturing the chassis and a single dedicated system board that can be ordered from online printed circuit board (PCB) assembly services. To promote accessibility, the project follows open hardware practices, such as design transparency, permissive licensing, accessibility in manufacturing methods, and comprehensive documentation. Semantic Versioning was incorporated to improve maintainability in development. Compared to the earlier versions, Robotont 3 maintains all the technical capabilities, while featuring an improved hardware setup to enhance the ease of fabrication and assembly, and modularity. The improvements increase the accessibility, scalability and flexibility of the platform in an educational setting

    Enhanced detection of freeze‒thaw induced landslides in Zhidoi county (Tibetan Plateau, China) with Google Earth Engine and image fusion

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    Freeze‒thaw induced landslides (FTILs) in grasslands on the Tibetan Plateau are a geological disaster leading to soil erosion. These landslides reduce biodiversity and intensify landscape fragmentation, which in turn are strengthen by the persistent climate change and increased anthropogenic activities. However, conventional techniques for mapping FTILs on a regional scale are impractical due to their labor-intensive, costly, and time-consuming nature. This study focuses on improving FTILs detection by implementing image fusion-based Google Earth Engine (GEE) and a random forest algorithm. Integration of multiple data sources, including texture features, index features, spectral features, slope, and vertical‒vertical polarization data, allow automatic detection of the spatial distribution characteristics of FTILs in Zhidoi county, which is located within the Qinghai‒Tibet Engineering Corridor (QTEC). We employed statistical techniques to elucidate the mechanisms influencing FTILs occurrence. The enhanced method identifies two schemes that achieve high accuracy using a smaller training sample (scheme A: 94.1%; scheme D: 94.5%) compared to other methods (scheme B: 50.0%; scheme C: 95.8%). This methodology is effective in generating accurate results using only ∼10% of the training sample size necessitated by other methods. The spatial distribution patterns of FTILs generated for 2021 are similar to those obtained using various other training sample sources, with a primary concentration observed along the central region traversed by the QTEC. The results highlight the slope as the most crucial feature in the fusion images, accounting for 93% of FTILs occurring on gentle slopes ranging from 0° to 14°. This study provides a theoretical framework and technological reference for the identification, monitoring, prevention and control of FTILs in grasslands. Such developments hold the potential to benefit the management of grassland ecosystem, reduce economic losses, and promote grassland sustainability

    Oil‐Infused Polymer Fiber Membranes as Porous Patches for Long‐Term Skin Hydration and Moisturization

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    Abstract Skin allergies and diseases, including atopic dermatitis (AD), affect millions worldwide. Current treatments for AD are often expensive, leading to a need for cost‐effective solutions. Here, using fiber‐based patches to maintain and increase skin hydration is explored, which helps treat eczema and AD. Nanofiber membranes are manufactured via electrospinning of eight different polymers: nylon 6 (PA6), polyimide (PI), poly(3‐hydroxybuty‐rate‐co‐3‐hydroxyvalerate (PHBV), poly(l‐lactide) (PLLA), polycaprolactone (PCL), and polystyrene (PS), and two molecular weights poly(vinyl butyral‐co‐vinyl alcohol‐co‐vinyl acetate) (PVB). Further, their morphology is examined through scanning electron microscopy (SEM), fibers, and pores diameter, wettability, and membrane thickness. Additionally, water vapor transmission rates (WVTR) are measured, and notably, skin hydration tests are conducted before and after using evening primrose oil‐infused patches. The comparison and findings highlight the flexibility of electrospun patches, demonstrating their potential in maintaining skin hydration for 6 h and enhancing skin moisture, which are necessary in AD treatment. These insights, which focus on selecting the most effective performance patches, help improve skin moisture, leading to tailored treatments for AD, which can significantly impact the efforts to reduce healthcare costs and simplify skincare steps

    Early diagnosis and treatment of perianal Crohn's disease in a 1‐year‐old infant: Case report and review of literature

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    Key Clinical Message Inflammatory bowel disease is rare in infants and it includes perianal Crohn's disease, which is inflammation at or near the anus. An early diagnosis is essential to prevent the complications that may affect the development and growth of the child

    Invasive cribriform carcinoma of the breast presenting as an erythematous papule on the nipple: A case report

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    Key Clinical Message Invasive cribriform carcinoma (ICC) is a rare form of invasive breast carcinoma with good prognosis. To date, case reports considering skin manifestations of ICC are scarce. We herein report a case of pure ICC presenting as an erythematous papule on the nipple with mammary Paget's disease in the epidermis. We aim to bring awareness to skin manifestation of ICC

    Autopsy findings in a rare case of pleomorphic carcinoma in a patient on dialysis

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    Key Clinical Message Pleomorphic lung cancer is a very rare type of cancer and very few cases have been reported in the literature. We present a case of pleomorphic lung cancer in a patient with history of IgA nephropathy on hemodialysis

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