REVIEW: DEVELOPMENT OF NATURAL MATERIALS AS BREAST CANCER ANTICANCER

Objective: This study aims to review various efforts in developing anticancer therapies based on medicinal plants and synthetic compounds, particularly for breast cancer, which has high prevalence and mortality rates. Method: Data were collected through a literature review of scientific journals published between 2010 and 2020. The study analyzed the potential of various medicinal plants and bioactive compounds using both experimental and computational approaches. Results: The review revealed that medicinal plants such as soursop leaves, galangal, moringa leaves, Kasumba Turate flowers, and red dragon fruit peels exhibit significant anticancer potential. Their activities include cytotoxicity, proliferation inhibition, and apoptosis induction in T47D and MCF-7 breast cancer cells. Additionally, an in silico approach was employed to evaluate bioactive compounds like galangin and quercetin, which demonstrated potential interactions with specific molecular targets such as HER-2 and SIRT1. Novelty: This study highlights the importance of exploring both natural and synthetic anticancer compounds to develop more effective and safer therapies. The integration of in silico analysis provides a deeper understanding of molecular interactions, supporting the advancement of targeted breast cancer treatments

AI in Personalized Medicine: Transforming Treatment Plans Through Precision Health

Integrating The application of AI in healthcare has advanced over the last decade and is most prominent in personalized medicine. Due to ML and DL algorithms, AI is helping in better prognosis, customized interventions, and better results in a number of health disorders. It seeks to offer customized treatment according to the various features of each patient, and not generic methods like were initially used. Big data is being incorporated with the help of AI in individualized medicine by using elements like genetics, past health records, and surroundings to constitute threats of diseases and recommend particular courses of treatment. This paper seeks to review the various aspects of AI in personalized medicine, the application of AI, the advantages of AI, the disadvantages of AI, and the future of AI in precision health

Manajemen Keperawatan

Manajemen keperawatan memiliki peran penting dalam memastikan pelayanan kesehatan yang efektif, efisien, dan berorientasi pada keselamatan pasien. Sistem pengelolaan yang baik dapat memberikan asuhan yang optimal serta meningkatkan mutu layanan kesehatan di berbagai fasilitas medis. Buku Manajemen Keperawatan disusun sebagai buku ajar yang membahas berbagai aspek dalam pengelolaan keperawatan, mulai dari perencanaan, pengorganisasian, pelaksanaan, hingga evaluasi dalam sistem pelayanan kesehatan. Pembahasan dalam buku ini mencakup kepemimpinan dalam keperawatan, pengelolaan sumber daya manusia, etika dalam praktik keperawatan, serta strategi dalam meningkatkan efisiensi layanan keperawatan. Selain itu, buku ini juga menguraikan tantangan yang dihadapi dalam dunia keperawatan dan bagaimana manajemen yang baik dapat membantu mengatasinya. Sebagai buku ajar, isi dalam buku ini dirancang agar dapat digunakan oleh siapa saja yang ingin memahami lebih dalam mengenai sistem pengelolaan keperawatan. Dengan bahasa yang jelas dan pembahasan yang sistematis, buku ini diharapkan dapat menjadi sumber belajar yang bermanfaat dalam meningkatkan keterampilan manajerial dalam bidang keperawatan

MENINGKATKAN KUALITAS BACAAN AL-QURAN MELALUI PEMBELAJARAN BERBASIS ANDRAGOGI

Buku ini menawarkan sebuah pendekatan inovatif dalam meningkatkan kemampuan membaca Al-Qur’an di kalangan orang dewasa dan lanjut usia. Di tengah tantangan rendahnya literasi Al-Qur’an di Indonesia, terutama di kalangan masyarakat dewasa, buku ini hadir sebagai solusi untuk memadukan prinsip-prinsip andragogi dengan metode pembelajaran Al-Qur’an. Pendekatan andragogi, yang berfokus pada karakteristik dan kebutuhan khusus orang dewasa dalam proses belajar, menjadi landasan utama dalam buku ini. Melalui analisis mendalam dan studi kasus yang relevan, buku ini mengeksplorasi berbagai model pembelajaran yang dapat diterapkan untuk meningkatkan keterampilan membaca Al-Qur’an secara tartil. Di dalamnya, pembaca akan menemukan strategi-strategi pembelajaran yang efektif, mulai dari perencanaan, pelaksanaan, hingga evaluasi pembelajaran, semuanya dirancang khusus untuk memenuhi kebutuhan pembelajaran orang dewasa. Buku ini tidak hanya memberikan teori, tetapi juga menawarkan panduan praktis bagi para pengajar dan pendidik yang ingin menerapkan pendekatan andragogi dalam kelas-kelas Al-Qur’an. Dengan bahasa yang mudah dipahami dan contoh-contoh aplikatif, buku ini sangat cocok bagi mereka yang terlibat dalam dunia pendidikan Al-Qur’an, baik di lembaga formal maupun non-formal. “Meningkatkan Kualitas Bacaan Al-Qur’an Melalui Pembelajaran Berbasis Andragogi” adalah bacaan wajib bagi para pendidik, pengajar, dan siapa saja yang peduli terhadap peningkatan literasi Al-Qur’an di kalangan masyarakat dewasa. Dengan pendekatan yang inovatif dan berbasis riset, buku ini diharapkan dapat menjadi salah satu solusi dalam meningkatkan kualitas bacaan Al-Qur’an di masyarakat, sehingga lebih banyak umat Islam yang mampu membaca, memahami, dan mengamalkan Al-Qur’an dengan baik

“Such is life”: A Marxist Attempt to Comprehend the “Injustice” and “Unfairness” of Capitalism in Peter Carey’s True History of the Kelly Gang

Marxism locates all forms of art within existing social conditions of economic and politics, even as it approaches the art-object as an important element within social relations through which particular meanings are standardized and held up as good taste in order to marginalize and ignore other meanings. Marxism sees this battle over meaning as reflecting a battle between dominant and oppressed sections of the society. The essence of the Marxism was undeniably the core of Karl Marx’s own intellectual trajectory throughout his life, and his friend and German philosopher Friedrich Engels brought the practice of Marxism as a concept into popularity. Marxism is inextricably associated with the idea of Capitalism where the bourgeoisie class of the society controls the means of production. The present approach of the paper is to inspect closely True History of the Kelly Gang by Peter Carey that describes the autobiographical narration of a real life Australian bushranger, Ned Kelly through the lens of Marxism with its emphasis on Capitalism. Ned Kelly wanted to write his life's historical account for his unborn daughter in order to reveal the truth and reality behind the injustices and enduring struggle that he suffered at the hand of the society. The physical existence of the Kelly family, especially Ned Kelly has been exploited by the wealthy and powerful people of the time. This study mainly aims to conceptualize Peter Carey’s True History of the Kelly Gang from a Marxist point-of-view. It proposes to understand the embedded features of Capitalism as well as different concepts associated with it in the novel True History of the Kelly Gang

Measurement of natural background radiation with time using geiger muller counter in Al-Qalam university Katsina

Radiation is a form of energy that travels through space at high speeds. Prolonged exposure to high levels of radiation can increase the risk of cancer later in life. This research introduces the use of a Geiger-Muller counter to measure indoor and outdoor natural background radiation levels at Al-Qalam University, Katsina, and compares the results with the national standard. The background radiation levels were measured at fourteen randomly selected locations. At each location, six readings were taken, and the average was used to calculate the natural background radiation exposure rate. The average indoor and outdoor doses were 0.227 µSv/h and 0.242 µSv/h, respectively. The findings indicate that the mean background radiation dose was below the globally recommended standard of 0.274 µSv/h. However, Gidan Hausa recorded a maximum value of 0.30 µSv/h, likely due to increased exposure to radioactive materials from laboratory activities

Analisis Keterampilan Berpikir Kritis Siswa Melalui Pendekatan Pembelajaran Berbasis Masalah

Critical thinking skills are essential competencies that must be possessed by students in facing the challenges of the 21st century. The Problem Based Learning Approach (PBL) is considered an effective method of developing this skill. This study aims to analyze students' critical thinking skills through the application of PBL in Junior High Schools in Cepu, Indonesia. This type of research is quantitative research with a quasi-experimental experimental approach. The data source in this study was a class VIII student of the two classes randomly selected as an experimental group and the control group. Data is collected using critical thinking skills tests given before and after pre-test (pre-test and post-test). The purpose of this study is to identify the extent to which the application of PBL can improve students' critical thinking skills. The results showed that there was a significant increase in students' critical thinking skills in the experimental group compared to the control group. The average post-test score of the experimental group increased significantly from 55 to 78, while the control group only increased from 56 to 62. T-test statistical tests showed a significance value of 0.001 (p <0.05). The results of this study support constructivist theory and social learning theory that emphasizes the importance of active learning and social interaction in the learning process. The application of PBL has proven effective in developing students' critical thinking skills, so it is recommended for educators toimplement this method in their learning.Keywords: Critical Thinking Skills, Problem -Based Learnin

EMPLOYEE ATTENDANCE APPLICATION AT UNIVERSITAS MUHAMMADIYAH SIDOARJO BASED ON WHATSAPP

Objective: Effective employee attendance management is crucial for optimizing operational efficiency in higher education institutions. This study aims to develop a WhatsApp-based attendance system to enhance accuracy, efficiency, and accessibility at Muhammadiyah University of Sidoarjo. Method: A web-based application was designed and integrated with the WhatsApp API, enabling employees to record attendance by sending messages via WhatsApp. The system includes automated data processing features for administrative monitoring. The research follows a system development life cycle (SDLC) approach, incorporating requirements analysis, design, implementation, and evaluation phases. Results: The implementation of the system demonstrated improved attendance efficiency, minimized human error in data recording, and reduced reliance on additional applications. The administrative panel facilitated real-time monitoring, enhancing managerial oversight. Novelty: This study presents an innovative approach by leveraging WhatsApp—a widely used communication platform—as a cost-effective alternative to conventional attendance systems. The integration of WhatsApp API eliminates the need for dedicated mobile applications, reducing maintenance costs and improving user adoption. This solution offers a practical model for universities seeking to modernize attendance management while maintaining ease of use for employees

Komputer Kuantum

Komputer kuantum adalah jenis komputer yang memanfaatkan prinsip-prinsip fisika kuantum, seperti superposisi dan entanglement, untuk melakukan perhitungan yang jauh lebih cepat dan lebih efisien dibandingkan dengan komputer tradisional. Di dalam komputer klasik, informasi disimpan dalam bit yang hanya bisa berada dalam dua keadaan, yaitu 0 atau 1. Sementara itu, di komputer kuantum, informasi disimpan dalam qubit yang dapat berada dalam beberapa keadaan sekaligus berkat fenomena superposisi. Dengan kemampuan ini, komputer kuantum dapat memecahkan masalah kompleks yang sulit atau bahkan tidak mungkin diselesaikan oleh komputer biasa, seperti simulasi molekul untuk pengembangan obat, optimasi proses industri, hingga pemecahan algoritma kriptografi yang aman. Namun, teknologi ini masih dalam tahap pengembangan dan menghadapi tantangan besar, termasuk kestabilan qubit dan kebutuhan untuk suhu yang sangat rendah agar qubit dapat berfungsi dengan baik. Meskipun begitu, kemajuan pesat dalam penelitian komputer kuantum menunjukkan potensi besar dalam revolusi teknologi di masa depan, yang dapat mengubah berbagai bidang, mulai dari ilmu pengetahuan hingga industri, dengan mempercepat pengolahan informasi dan pemecahan masalah yang lebih kompleks

EFFECTS OF SOCIO-ECONOMIC DEVELOPMENT CHALLENGES ON RURAL COMMUNITIES IN NIGERIA: A EXPOSITORY STUDY OF ODUGBO COMMUNITY IN APA LGA OF BENUE STATE, NIGERIA

Objective: Rural communities in Nigeria face various socio-economic development challenges that hinder their progress and well-being. This study examines the effects of these challenges, particularly in Odugbo community, located in Apa Local Government Area of Benue State, Nigeria. The research aims to identify key socio-economic barriers and propose strategies for sustainable development. Method: This study is based on the Social Capital Theory and employs a mixed-methods approach, combining both qualitative and quantitative research. Primary data were collected through questionnaires administered to 350 randomly selected participants, including community members and relevant stakeholders. Secondary data were obtained from literature, reports, and other documentary sources. The mean scores were used for analyzing research questions, while content analysis was applied to secondary data. Results: Findings indicate that inadequate infrastructure, limited access to healthcare and education, poor road networks, high poverty rates, and limited economic opportunities are significant socio-economic challenges in the Odugbo community. The study also highlights various strategies to address these issues, including community engagement, access to financial services, external support and partnerships, government policies, and awareness creation. Novelty: This study contributes to existing literature by providing an in-depth analysis of socio-economic challenges in a specific rural Nigerian community and proposing localized strategies for sustainable development. The findings emphasize the importance of community-driven initiatives and external collaborations to overcome socio-economic barriers