ROLE OF ACCUMULATED LIPID DROPLETS IN DROSOPHILA MACROPHAGES DURING BACTERIAL INFECTION

Macrophages are white blood cells of the immune response, in mammals, fruit flies, and most animals. They are important for Fighting infections in many ways including phagocytosis and production of inflammatory signals. Curiously, in many inflammatory conditions, macrophages often accumulate lipids in the form of lipid droplets, although the purpose of this accumulation is not well understood. I have used the fruit fly Drosophila melanogaster to investigate the purpose of macrophage lipid droplets and have found the lipids are essential to allow the differentiation of the macrophages into a specialized form called “lamellocytes”, which is a very large and flattened cell type. Additionally, I found that one way that lipid droplets promote lamellocyte differentiation is by supplying the lipids needed to make the plasma membrane of the enormous lamellocytes

GEOLAB - CLARIFIER project

The existing Critical Infrastructure (CI) of Europe in the water, energy, urban and transport sector is facing major challenges because of pressures such as climate change, extreme weather, geo-hazards, ageing and increased usage, in combination with pivotal changes in the CI to meet long-term societal goals (e.g., energy transition). To address these challenges, scientific research and innovative solutions are needed that can only be achieved by an interdisciplinary, cross-boundary approach and by equipping expert teams with the most advanced suite of physical research infrastructure available. This will allow them to work across spatial scales, explore different theories that describe the pressures and adopt innovative techniques in the development of practical solutions. The GEOLAB Research Infrastructure (RI) consists of 11 unique installations in Europe developed to study subsurface behavior and the interaction of the subsurface with structural CI elements (e.g., a bridge) and the environment. The overarching aim of GEOLAB is to integrate and advance these key national research infrastructures towards a one-stop-shop of excellent physical research infrastructure specifically for performing ground-breaking research and innovation to address the challenges faced by the CI of Europe. During the GEOLAB Transnational Access (TA), users outside the consortium gain access to the GEOLAB installations to perform research and innovation. One of the GEOLAB’S TA projects is the project CLARIFIER. For this project, centrifuge tests were conducted at Deltares, in The Netherlands. The main objectives of the CLARIFIER tests are: (a) to evaluate how well partially decomposed fibrous peat can be modelled in a geotechnical centrifuge and to (ii) understand the failure mechanisms under light weight embankments

TARL-41CE19-424-221

Gahagan biface from the George C. Davis site

Data and metadata of crop yield and quality derived from H2020 Diverfarming project

Data and metadata of crop yield and quality from different cases studies and long terms from WP3 "Crop production and quality", derived from H2020 Diverfarming project. This workpackage provides robust and sound data about how diversified cropping systems with low-input practices and efficient use of resources have positive effects on crop production and quality, and so, farm yields and economic revenues for farmers is increased. This can increase trading productivity with high quality outputs, so improving the competitiveness of European agriculture in the global market. http://www.diverfarming.eu

Ten new species in Papuliscala de Boury, 1911 (Gastropoda, Epitoniidae) from the South Azorean Seamount Chain

Eleven species of the genus Papuliscala de Boury, 1911 (Epitoniidae Berry, 1910) were collected on the South Azorean Seamount Chain (SASC), ten of them described as new: Papuliscala dictyophora n. sp., P. seamountae n. sp., P. platoensis n. sp., P. carolienae n. sp., P. luuki n. sp., P. daani n. sp., P. meteorica n. sp., P. atlantisa n. sp., P. vixcostata n. sp. and P. mikra n. sp. The distributions of these new taxa are probably restricted to summital plateaus and bathyal slopes of the SASC. Some of them form regional radiations within Papuliscala with shared morphological characteristic

Impacts of the four-day school week on early elementary achievement

© This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/. Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailing [email protected]

Multi-vehicle interaction safety of connected automated vehicles in merging area: A real-time risk assessment approach

© This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/. Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailing [email protected]

Book Review: Scanning the Pharaohs

Book Review: Hawass, Zahi & Saleem, Sahar N.: Scanning the Pharaohs: CT Imaging of the New Kingdom Royal Mummies, Cairo (The American University in Cairo Press) 2016, Edited by Sue D’Auria, Foreworded by David O’Connor, 318 + xviii pages, ISBN 978–977–416–673–0

EFFECTS OF SURFACE MODIFICATION ON A PROTON EXCHANGE MEMBRANE FOR IMPROVEMENTS IN GREEN HYDROGEN PRODUCTION

Proton Exchange Membrane (PEM) electrolysis, an advanced technique for producing hydrogen with efficiency and environmental friendliness, signifies the forefront of progress in this domain. Compared to alkaline cells, these electrolytic cells offer numerous advantages, such as lower operating temperatures, enhanced hydrogen production efficiency, and eliminating the need for an aqueous solution. However, PEM electrolysis still faces limitations due to the high cost of materials used for the membrane and catalysts, resulting in elevated expenses for implementing large-scale systems. The pivotal factor in improving PEM electrolysis lies in the Platinum catalyst present on the membrane surface. Enhancing catalytic efficiency through various methods and advancements holds immense significance for the progress of this technology. This study investigates the use of patterned membranes to improve the performance of PEM electrolytic cells toward green hydrogen production. By increasing the Platinum loading across the membrane surface and enhancing catalytic performance, these patterned membranes overcome challenges faced by conventionally fabricated counterparts. The findings of this research indicate that membranes with modified surfaces not only exhibit higher current draw but also achieve elevated rates of hydrogen production

EJPSOIL CarboSeq crop and soil management database

The database of the EJPSOIL CarboSeq WP2 with (meta)data of long term agricultural field experiments for Tier2 (SOC) and where available Tier 3 (carbon input) from EuropeThe empty template of the database used to collect the (meta)data is available at 10.5281/zenodo.809488