Development of professional tolerance in medical students through professionally-oriented foreign language training

Global sociocultural transformations in the modern world are associated with expansive digitalisation and its impact on human life. Given the advantages of digital technology development, a number of significant problems arise, in particular, social differentiation, commercialisation of socionomic professions, information consumerism, emotional estrangement due to the virtualisation of communication, a shift in value orientations, replacement of traditional moral norms with their destructive simulacra. There is a clear need for intensification of educational activities in higher education focused on the humanisation of public consciousness, the promotion of social cohesion and the development of the moral backbone of an individual. Hence, it is necessary to refer to the theoretical and methodological foundations of tolerance development in students. The aim of this article is to clarify the concept of professional tolerance of a doctor and describe the strategy of its development in students in the process of foreign language training. Considering the issue of professional education of future doctors, the authors note that the vector of students’ spiritual and moral development is determined by the values, attitudes, and norms of medical ethics and deontology. Herewith, the principle of tolerance is of the basic ones since professional medical practice is based on regular interpersonal interaction. The authors define the concept of a doctor’s professional tolerance as the willingness to provide patients with high-quality medical care regardless of the heterogeneity of socio-cultural factors and subjective personal aspects. This concept assumes the doctor’s tact, empathy, psychological flexibility and poise. The proposed strategy for the development of professional medical tolerance in students via professionally-oriented foreign language training involves the holistic formation of its cognitive, affective and conative components through the educational content and the parity in subject-subject interaction. In the development of the cognitive component, considerable importance is ascribed to supplementing the basic educational materials by authentic content of social and professional orientation. The connecting link of the development of cognitive and affective components is the identification and levelling of stereotypes and prejudices regarding socially significant diseases. The basis for the development of the affective component is pedagogical tolerance, a favourable educational environment, interactive activities at classes, and the facilitation of students’ reflection. The development of the conative component of tolerance is directly tied to the development of professional communicative competence of future doctors: the study and development of various speech clichés in the format of interaction with patients; revision of politeness formulas; practicing non-verbal communication means in playing out quasi-professional situations; mastering the speech norms “plain language” and “people-first language”

Synthesis of novel hierarchical micro/nanostructures AlOOH/AlFe and their application for As(V) removal

Hierarchical micro/nanostructured composites, which contain iron and/or its (hydr)oxides, demonstrate high rate and capacity of arsenic adsorption. The main objective of this paper is the use of novel low toxicity AlOOH/AlFe hierarchical micro/nanostructures for arsenic removal. AlOOH/AlFe composite was obtained by simple water oxidation in mild conditions using AlFe bimetallic nanopowder as a precursor. AlFe bimetallic nanopowder was produced by electrical explosive of two twisted wires in argon atmosphere. The productivity of the electrical explosion assembly was 50 g/h, with the consumption of the electrical energy was 75 kW·h/kg. AlFe bimetallic nanoparticles were chemically active and interacted with water at 60 °C. This nanocomposite AlOOH/AlFe is low cost and adsorbs more than 200 mg/g As(V) from its aqueous solution. AlOOH/AlFe composite has flower-like morphology and specific surface area 247.1 m2/g. The phase composition of nanostructures is present AlOOH boehmite and AlFe intermetallic compound. AlOOH/AlFe composite was not previously used for this. The flower-shape AlOOH morphology not only facilitated deliverability, but increased the As(V) sorption capacity by up to 200 mg/g. The adsorption kinetics has been found to be described by a pseudo-second-order equation of Lagergren and Weber-Morris models while the experimental adsorption isotherm is closest to the Freundlich model. This indicates the energy heterogeneity of the adsorbent surface and multilayer adsorption. The use of non-toxic nanostructures opens up new options to treat water affected by arsenic pollution

Study on a conceptual model for campus transformation of classical universities in the digital era

This article presents a conceptual management model of campus space 4.0 (CS4.0), in which CS4.0 is viewed as a condition for the transformation of classical universities in the digital era. To create this model, we used the systems approach as well as complexity theory, focusing on the ontological, spatial, axiological, social, psychological, and management aspects. The model not only defines the systems status of CS4.0 and describes the three types of properties inherent in CS4.0. This model also explains why, in the digital era, CS4.0 can become the agent of change for a classical university that has had a long history. This model of CS4.0 will not destroy the university’s cultural identity and academic values; rather, it will serve the interests of all groups within the university community. This conceptual model can be the key to understanding one of the possible management strategies for the development of the classical university in the digital network society at the beginning of the Fourth Industrial Revolution

Development of sers substrates based on nanoparticles obtained by pulsed laser ablation

SERS spectroscopy is an effective method for the determination of organic and biological compounds, which finds its place in many areas of human life: the analysis of works of art and food 24 YOUNG SCIENTISTS SESSION SESSION Y products, the identification of drugs and drugs, the study of biological structures, incl. at the cellular level. The creation of simple and effective SERS substrates is an urgent task in the development of this method. This paper presents the results of a study of SERS substrates based on gold nanoparticles (NPs). Gold NPs were obtained by pulsed laser ablation of an Au metal target in alcohol using a Nd:YAG laser (1064 nm, 7 ns, 150 mJ). The resulting colloidal solution was applied onto glass substrates by the drop method, varying the number of layers. The SERS characteristics were studied using a model dye rhodamine 6G using Renishaw inVia Basis Raman microscope. The samples were excited in the region of surface plasmon resonance of gold by laser radiation of 532 nm. The results of the study showed that with an increase in the number of deposited layers up to 5, the intensity of the Raman scattering of the dye increases linearly. With a further increase in the number of layers, the signal saturates. This data correlates with SEM data. At the beginning, an increase in the packing density of NPs in the plane of the substrate is observed. Accordingly, the number of "hot spots" increases, which contribute to the amplification of the signal. Further, the homogeneity of the NP layer deteriorates, and large bulk agglomerates appear. Thus, we have developed a simple method for obtaining SERS substrates, which made it possible to increase the signal intensity up to three orders of magnitude

Optimal pumping parameters of a copper vapor laser under breakdown conditions

The active medium of pulsed-periodic copper vapor lasers (CVL) is characterized by a high prepulse electron concentration ne0 1013 cm–3. Therefore, it was assumed that the development of the discharge under these conditions is carried out without the breakdown stage. However, as studies have shown, the development of a discharge in gas discharge tubes (GDT) with electrodes located in cold buffer zones (CBZ) is carried out with a breakdown stage

Reprogrammed CD8+ T-lymphocytes isolated from bone marrow have anticancer potential in lung cancer

CD8+ T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes largely limits the effectiveness of therapy. In this study, reprogrammed T-lymphocytes used MEK inhibitors and PD-1 blockers to increase their antitumor activity. Antitumor effects of reprogrammed T-lymphocytes were shown in vitro and in vivo in the Lewis lung carcinoma model. The population of T- lymphocytes with persistent expression of CCR7 was formed as a result of reprogramming. Reprogrammed T-lymphocytes were resistant to apoptosis and characterized by high cytotoxicity against Lewis lung carcinoma (LLC) cells in vitro. Administration of reprogrammed T-lymphocytes to C57BL/6 mice with LLC reduced the number of lung metastases. The antitumor effect resulted from the elimination of tumor cells and cancer stem cells, and the effect of therapy on cytotoxic T-lymphocyte counts. Thus, reprogramming of T-lymphocytes using MEK inhibitors is a promising approach for targeted therapy of lung cancer