Biblometric Analysis of the Effect of Type II Diabetes Mellitus on Immunity

Type 2 diabetes mellitus is the inability of the body's cells to respond to insulin or so-called insulin resistance which causes hyperglycemia. The body's immune system is a complex system that functions to protect the body from various diseases and infections. This research was conducted with the aim of applying bibliometric methods using quantitative analysis to trace the development of research related to type 2 Diabetes Mellitus. This study uses a biblometric analysis method that can help researchers in studying the content of bibliography, citation analysis of each article taken from the lens database. The results of data with the keywords DM type 2, immune, and complication are not too much, only about 475 data were obtained, and after being identified and cleaned using vosviewer, data was obtained in the form of several clusters such as images

Incidence of Cefixime Resistance in Patients with Chronic Kidney Disease at Harapan Keluarga Hospital

Antibiotic resistance is an increasing global health challenge, especially in patients with advanced chronic kidney disease (CKD). This study aims to investigate cefixime resistance in patients with stage 4-5 CKD at Harapan Keluarga Hospital with a retrospective cohort design using medical record data. Chi-squared test analysis showed a significant association between cefixime resistance and advanced CKD (χ² = 34.714, p = 0.003). The results showed a higher prevalence of cefixime resistance in male patients (60%), antibiotic use of more than 14 days (65%), and hospitalization of more than five days (80%). The mechanism of resistance involves beta-lactamase production and changes in the gut microbiota due to dysbiosis. Factors such as irrational antibiotic use, length of hospital stay, and catheter use contributed to higher resistance. This study highlights the need for evidence-based antibiotic stewardship strategies to reduce resistance, especially in vulnerable populations such as patients with advanced CKD. Scientific implications include the development of more effective infection management strategies, close monitoring of antibiotic use, dose adjustment according to CKD severity, and education of health care workers to increase awareness of antibiotic resistance. This study contributes to efforts to prevent antibiotic resistance in the advanced CKD population

The Effect of Giving Ethanol Extract of Palm Fruit (Arenga pinnata Merr.) on Morphology and Liver Function of White Rats (Rattus norvegicus L.) Induced by Carbon Tetrachloroide

Carbon tetrachloride is well known as hepatotoxic, including toxic substances commonly used to induce liver damage. Sugar palm (Arenga Pinnata Merr.) is a type of palm plant that is used as a source of antioxidants, one of which is part of the fruit. The aim of this research is to determine the effect of administering ethanol extract of palm fruit (Arenga pinnata Merr.) on the morphology and liver function of rats (Rattus norvegicus L.) which is induced by carbon tetrachloride. This research method used a completely randomized design consisting of 20 mice grouped into 5 groups, namely negative control, positive control, P1 (ethanol extract of palm fruit 90 mg/kg BW), P2 (180 mg/kg BW), P3 (360 mg /kg BW) with each group having four repetitions. Data analysis was carried out using the One Way ANOVA test and continued with the Duncan test. The results of this study show that carbon tetrachloride at a dose of 1 mL/kg BW can damage the morphological appearance of rat liver and increase SGOT and SGPT levels. Giving ethanol extract of palm fruit to the P3 group at a dose of 360 mg/kg BW was the most effective dose to improve liver morphology and reduce SGOT and SGPT levels in white rats induced by carbon tetrachloride

Analysis of Pteridophyta Plants Vegetation in Amporiwo Forest Area, Poso District

Another role of ferns is as a source of plasma nutfah and also has the potential as a source of food and medicine. Analysis of pteridophyta plant vegetation aims to describe the types of Pteridophyta plants in the Amporiwo forest area. The type of research used in this study is a qualitative approach. The population and samples in this study were all types of ferns found in the Amporiwo forest area. Data analysis used a google lens camera and a reference book on Identification of Ferns (Pteridophyta). The results of the study showed that there were types of ferns (pteridophyta) with details of 5 orders, 9 families and 17 species, namely Pyrrosia lanceolata, Phymatosorus scolopendria. Pyrrosia piloselloides, Diplazium esculentu., Drynaria quercifolia, Christella leveille, Thelypteris pectiniformis, Asplenium nidus L., Nephrolepis biserrata, Pteridium esculentum, Dicranopteris linearis, Stenochlaena palustris, Dyplazium sorgonens, Ligodium palmatum, Lycopodiella cernua, Hipoderris brownie, Asplenium Polyodon. The conclusion is that the types of Pteridophyta plants in the Amporiwo forest area were found to be 5 orders, 9 families, and 17 species

HUBUNGAN ANTARA AKTIVITAS ANAK PADA PENGGUNAAN METODE BERNYANYI DENGAN KEMAMPUAN MENGHAFAL ASMAUL HUSNA ANAK USIA DINI

Berdasarkan hasil studi pendahuluan di Kelompok B1 RA Al-Mukhlisin 2, Kecamatan Bojongsoang, Bandung, menunjukkan bahwa metode bernyanyi sering digunakan dan membuat anak-anak antusias. Namun, kemampuan menghafal Asmaul Husna anak belum optimal, dengan beberapa anak masih ragu mengurutkannya dan mengulang hafalan. Penelitian ini bertujuan mengetahui (1) aktivitas bernyanyi anak, (2) kemampuan menghafal Asmaul Husna, dan (3) hubungan antara keduanya. Metode bernyanyi dianggap efektif dalam pendidikan Islam, membantu mengungkapkan pikiran dan perasaan anak, serta menghafal membutuhkan memori yang kuat. Penelitian korelasional ini melibatkan 18 anak dengan teknik total sampling, menggunakan observasi, wawancara, dan dokumentasi untuk mengumpulkan data. Hasil menunjukkan aktivitas bernyanyi anak rata-rata bernilai 80 (sangat baik), sedangkan kemampuan menghafal Asmaul Husna bernilai rata-rata 59 (kurang). Hubungan antara kedua variabel dihitung dengan korelasi product moment, menghasilkan r sebesar 0,77 (tinggi). Uji hipotesis menunjukkan t_hitung = 4,813 > t_tabel = 2,120, dengan kontribusi 59,29%. Hipotesis nol ditolak, hipotesis alternatif diterima, menunjukkan hubungan signifikan antara aktivitas bernyanyi dan kemampuan menghafal Asmaul Husna di Kelompok B1 RA Al-Mukhlisin 2

Analisis Kebutuhan Pengembangan Model Pembelajaran Chemistry Real Integrated Laboratory Work (CHEM-RILW) Pada Pembelajaran Kimia

This study aims to analyze the need for further development of the CHEM-RILW model, an extension of the previously developed ILW model. The respondents involved in this study included two lecturers (N = 2) and forty-seven chemistry students (N = 47). Data was collected using observation sheets, questionnaires, critical thinking tests, and rubrics for argumentation and communication skills. The results indicated that the implementation of the learning process successfully integrated investigative activities carried out in the laboratory. This integration demonstrated that the pre-laboratory, laboratory, and post-laboratory stages were effectively implemented. However, the previous model did not sufficiently enhance students' interpretation and presentation skills. Additionally, the human element was not adequately emphasized, which limited the development of students' argumentation skills. Analysis of the lecturer questionnaire revealed a need to improve the learning model by incorporating more real-world applications of theory. Based on these findings, it is clear that further development of the ILW model is necessary. The CHEM-RILW model, as an enhancement, introduces real-world aspects and emphasizes the human element in learning, highlighting the relevance of community science in the context of chemistry concepts.Penelitian ini bertujuan untuk melakukan analisis kebutuhan pengembangan model CHEM-RILW sebagai bagian dari model ILW yang sebelumnya telah dikembangkan. Responden yang terlibat dalam penelitian ini adalah dosen (N =2) dan mahasiswa kimia (N = 47). Pengumpulan data dilakukan dengan lembar observasi, kuesioner, tes berpikir kritis, rubrik keterampilan argumentasi dan komunikasi. Hasil penelitian menunjukkan bahwa pelaksanaan pembelajaran telah terintegrasi dengan pelaksanaan penyelidikan yang dilaksanakan di laboratorium. Integrasi ini menunjukkan tahap pra-laboratory, laboratory work, dan post-laboratory telah dilaksanakan dengan optimal. Namun, model sebelumnya belum mampu meningkatkan keterampilan interpretasi dan presentasi. Faktor elemen manusia belum terlalu dimunculkan sehingga argumentasi mahasiswa juga belum terlatih dengan baik. Analisis kuesioner dosen menunjukkan perlunya penyempurnaan model pembelajaran dengan lebih banyak melibatkan aplikasi real dari teori. Berdasarkan hasil analisis ini maka diperlukan pengembangan model ILW yang sebelumnya telah dikembangkan. Pengembangan model CHEM-RILW menunjukkan tambahan aspek real pada model ILW untuk memasukkan elemen manusia dalam pembelajaran. Konsep real menekankan pada deskripsi sains asli masyarakat yang dapat menunjukkan elemen manuasia dalam konsep kimia

Effect Differences Depth on Chlorophyll Content (Kappaphycus alvarezii) Seaweed Tissue Culture Cultivated in The Waters of Gerupuk Bay

Seaweed developed through tissue culture techniques has several advantages, such as high carrageenan content, rapid growth, and resistance to disease. In seaweed cultivation, growth is influenced by photosynthetic pigments such as chlorophyll. Chlorophyll plays an important role in converting sunlight into chemical energy needed for growth. This study aims to analyze the chlorophyll content in Kappaphycus alvarezii cultivated at different depths in Gerupuk Bay waters. This study used an experimental method with a completely randomized design (CRD) consisting of 4 treatments and 3 replications, namely depths of 0 cm (P1), 5 cm (P2), 10 cm (P3), and 15 cm (P4). Results of this study indicate that planting at different depths can increase the absolute weight of K. alvarezii tissue culture ranging from 283 g to 356 g, specific growth rate between 5.72%/day to 5.91%/day, seaweed production ranging from 661 g/m2 to 832 g/m2, chlorophyll content between 5.60 mg/L to 21.89 mg/L, and phycoerythrin content between 0.027 mg/L to 0.19 mg/L. The conclusion is that the cultivation of K. alvarezii tissue culture with floating rafts at different depths can affect growth and yield. Cultivation of K. alvarezii seaweed at a depth of 0 cm using the floating raft method gave the best results, namely increasing absolute weight up to 356 g, specific growth rate up to 5.91%/day, and production up to 832 g/m2, supported by chlorophyll content of 21.89 mg/L and phycoerythrin content of 0.195 mg/L. For optimal production results, it is recommended to use a depth of 0 cm in floating raft seaweed cultivation

Twenty-Five Years Research on Micropropagation of Stevia and Curcuma sp. and Improving Secondary Metabolites using Precursor-elicitor in vitro: A Review

In vitro culture technique is an effective method for plant propagation to overcome the limitations of conventional cultivation. This method is used to improve accumulation of plant secondary metabolites. The purpose of this study is to review the development of micropropagation and improving secondary metabolites in Stevia rebaudiana and Curcuma plants through the application of precursors and elicitors. The systematic literature review is used to analyse scientific articles or publications from 2000 to 2025 obtained from various online databases using relevant keywords. The results showed that Stevia was more studied when compared to Curcuma due to its high economic value, with significant impact on the study of improving accumulation of stevioside and rebaudioside production through several elicitor and precursors. In Curcuma, beside in vitro culture for mass propagation, the response to in vitro treatment of elicitor dan precursors were varied, but some precursors such as phenylalanine were shown to improve curcuminoid accumulation. In conclusion, tissue culture techniques and the use of elicitor and precursor for improving secondary metabolites accumulation have the potential impact to support mass propagation, production and sustainable optimization of plant bioactive compounds

Optimizing Idle Land Utilization to Enhance Local Food Security in Banjarbaru City

The ongoing land-use conversion in Banjarbaru City has significantly reduced agricultural areas, potentially threatening local food availability and the achievement of food security. This study aims to identify the distribution of idle land and assess its potential utilization as an alternative for agricultural development in urban areas. The methodology integrates drone imagery for mapping uncultivated land, agricultural and biophysical statistical data, and community perception surveys to evaluate readiness and constraints in managing idle land. The results show that idle lands are spread across all districts, with the highest concentration in South Banjarbaru and Landasan Ulin. These areas exhibit high potential for the development of horticultural crops and lowland rice cultivation, although technical interventions such as soil rehabilitation and improved water access are required. In conclusion, optimizing the utilization of idle land in Banjarbaru City can serve as an effective strategy to enhance local food production and strengthen area-based food security.

Edukasi Berbicara Bahasa Indonesia di SD Negeri 41 Kabupaten Kaur

Artikel ini membahas kegiatan sosialisasi yang bertujuan untuk meningkatkan keterampilan berbicara bahasa indonesia yang baik dan benar pada siswa di SDN 41 Kabupaten Kaur melalui pengajaran Bahasa Indonesia. Dalam menghadapi tantangan seperti kurangnya kepercayaan diri siswa dan minimnya fasilitas, kegiatan ini menerapkan metode pembelajaran interaktif, termasuk diskusi kelompok dan permainan peran. Hasil penelitian menunjukkan bahwa penerapan metode ini berhasil meningkatkan kepercayaan diri siswa, memperluas kosakata, dan kemampuan berbicara di depan umum. Peran aktif guru dalam memberikan umpan balik konstruktif dan menciptakan lingkungan belajar yang positif terbukti efektif dalam mendukung proses pembelajaran. Keterlibatan orang tua juga diakui sebagai faktor penting dalam mendukung perkembangan keterampilan berbicara siswa. Temuan ini menunjukkan bahwa dengan pendekatan yang tepat, keterampilan komunikasi siswa dapat ditingkatkan secara signifikan, mempersiapkan mereka untuk menghadapi tantangan di era globalisasi