Framorando_Perozzo_Social_Comparison_And_Effort

Data and data coding of the experiment reported in: David Framorando & Delia Perozzo When Social Comparison Works as Demotivator: Stronger Peers Mitigate Levels of Effor

Excitation-Wavelength Dependent Photophysics of a Torsionally Disordered Push-Pull Dye

Data presented in: 'Excitation-Wavelength Dependent Photophysics of a Torsionally Disordered Push-Pull Dye', I. Fureraj, J. Wega, E. Balanikas, K. K. P. Pamungkas, N. Sakai, S. Matile and E. Vauthey, J. Phys. Chem. Lett. (2024), 15, 7857-7862 https://doi.org/10.1021/acs.jpclett.4c0184

In vitro screening of UGT2B10 in silico prioritized putative ligands from drugs used in the pediatric hematopoietic stem cell transplantation setting

Screening in vitro of acetaminophen, lorazepam, mycophenolic acid and voriconazole N-oxide to assess the potential of being substrates and/or inhibitors of UGT2B1

Oxidation-sensitive cysteines drive IL-38 amyloid formation

IL-38 regulation during oxidative stres

Dataset for Enantiopure Boramidine for Detailed (Chir)Optical Studies

Inclusion of boron atoms into chiral π-conjugated systems is an effective strategy to unlock unique chiroptical properties. Herein, preparation and characterization of a configurationally stable axially-chiral boramidine are reported showcasing absorption in the UV domain, deep-blue fluorescence (Φ up to 94%), and ca. |10-3| gabs and glum values. Detailed photophysical studies and quantum-chemical calculations elucidate the deactivation pathways of the emissive state to the triplet excited states, involving increased spin-orbit coupling between S1 and T3

Raw datasets - Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients

The worldwide increase in obesity and type 2 diabetes (T2D) represents a major health challenge. Chronically altered lipids induced by obesity further promote the development of T2D, and the accumulation of toxic lipid metabolites in serum and peripheral organs may contribute to the diabetic phenotype. To better understand the complex metabolic pattern of lean and obese T2D and non-T2D individuals, we analysed the lipid profile of human serum, skeletal muscle and visceral adipose tissue of two cohorts by systematic mass spectrometry-based lipid analysis.Lipid homeostasis was strongly altered in a disease- and tissue-specific manner, allowing us to define T2D signatures associated with obesity from those that were obesity independent. Lipid changes encompassed lyso-, diacyl- and ether-phospholipids. Moreover, strong changes in sphingolipids included cytotoxic 1-deoxyceramide accumulation in a disease-specific manner in serum and visceral adipose tissue. The high amounts of non-canonical 1-deoxyceramide present in human adipose tissue most likely come from cell-autonomous synthesis because 1-deoxyceramide production increased upon differentiation to adipocytes in mouse cell culture experiments. Taken together, the observed lipidome changes in obesity and T2D will facilitate the identification of T2D patient subgroups and represent an important step towards personalized medicine in diabetes

Dataset for Pd-Catalyzed [3+6+3+6] Macrocyclizations of Aryl alpha-Diazo-beta-Ketoesters

Thanks to Pd(II)-catalysis, an efficient synthesis of unsaturated macrocycles is achieved by [3+6+3+6] condensation of cyclic ethers with aryl alpha-diazo-beta-ketoesters. The presence of the electron-rich aryl ester moieties forbids the use of dirhodium complexes as these diazo decomposition catalysts provoke unforeseen intermolecular Csp2-H insertion reactions that derail the targeted reactivity. With Pd(acac)2, using high concentration conditions (1 M), a variety of 18-membered macrocycles (16 examples) is however afforded with both aryl and alkyl diazo reagents. Catalyst selection for either electrophilic aromatic substitution (Rh) or ylide (Pd) pathways are explained by computational approaches

SACS-FR - Staff Attitude to Coercion Scale version française

Traduction française de l'échelle SACS "Staff Attitude to Coercion Scale" avec l'aimable autorisation des auteurs de la version originale Tonje Lossius Husum et Torleif Ruud. Cette échelle est composée de 15 items et consiste en une série d'affirmations sur l'utilisation de la contrainte

SNF Project 100014_185348 “Affective Influences on Goal Pursuit: The Moderating Role of Deliberation”

Data of Unpublished Experiments (UEs

Correlative imaging of ferroelectric domain walls

The wealth of properties in functional materials at the nanoscale has attracted tremendous interest over the last decades, spurring the development of ever more precise and ingenious characterization techniques. In ferroelectrics, for instance, scanning probe microscopy based techniques have been used in conjunction with advanced optical methods to probe the structure and properties of nanoscale domain walls, revealing complex behaviours such as chirality, electronic conduction or localised modulation of mechanical response. However, due to the different nature of the characterization methods, only limited and indirect correlation has been achieved between them, even when the same spatial areas were probed. Here, we propose a fast and unbiased analysis method for heterogeneous spatial data sets, enabling quantitative correlative multi-technique studies of functional materials. The method, based on a combination of data stacking, distortion correction, and machine learning, enables a precise mesoscale analysis. When applied to a data set containing scanning probe microscopy piezoresponse and second harmonic generation polarimetry measurements, our workflow reveals behaviours that could not be seen by usual manual analysis, and the origin of which is only explainable by using the quantitative correlation between the two data sets