Processing and Ductile-Brittle Transitions in PM Manganese Steels

YesBrittleness in manganese steels can be associated with processing in a "wet¿ [micro]climate resulting in the formation of continuous oxide networks. The formation of these networks can be prevented by sintering in an atmosphere, also ¿local¿ in a semiclosed container, adhering to the Ellingham-Richardson oxide reduction criteria. When this requirement is satisfied, however, further types of ductile ¿ brittle transitions are observed. Rapid cooling, typically above 40°C/min, produces enough martensite to render Fe-(3-4)Mn-(0·6-0·7)C material macroscopically brittle. Quenched and conventionally tempered structures remain brittle. It is tentatively suggested that segregation of minor alloying/tramp element(s), as in cast materials, is responsible for this temper embrittlement. To overcome it, heat treatment at a temperature no higher than 200°C, recovery/stress relief, is recommended

Policy Reform and the Economic Development of Tanzania.

This paper reviews the long-term economic performance of Tanzania since independence using long-term series of key economic and social indicators constructed from a variety of sources. The disastrous export performance for most of the period under consideration can be attributed partly to domestic policy failures and partly to a hostile external environment. However inconsistent donor support to a highly aid dependent economy at times exacerbated the constraints imposed by persistent foreign exchange shortages. Greater stability in funding and a more flexible policy dialogue are needed. The extent to which a small and poor economy with a weak indigenous private sector can rely on foreign private investment to finance investment in the early stages of adjustment is questioned. Investment in human capital beyond primary school level is also needed if growth is to be sustained

Optimisation of intact cell MALDI method for fingerprinting of methicillin-resistant Staphylococcus aureus

NoThe use of matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry on intact cell microorganisms, Intact Cell MALDI (ICM), has been shown by numerous workers to yield effective species level identification. Early work highlighted the significant effect that variation in culture media, incubation conditions and length of incubation had on the spectra produced. Therefore, in order to achieve reliable and reproducible species level identification and sub-typing of microorganisms from ICM fingerprints, it has been essential to develop standardised methods. For methicillin-resistant Staphylococcus aureus (MRSA), a major nosocomial pathogen, we have developed such a standardised method. In this paper we present the experimental parameters, namely, the incubation period, the number of passages required from lyophilised or stored isolates, the method of deposition of the bacterial cells, the concentration of matrix solution, the drying time of bacterial cells prior to the addition of the matrix solution, the time between preparation of the bacterial/matrix sample and analysis and the MALDI pulsed extraction setting, which were considered during the development of defined methods

Managing functional diversity to improve the performance of international joint ventures.

NoInternational Joint Ventures (IJVs) have become one of the most important ways for companies to expand their activities and exploit business opportunities abroad. In China, for example, which has become the world's largest recipient of Foreign Direct Investment, IJVs with local companies are the most important way of doing business. However, many companies have learnt that the performance of their joint ventures in China does not meet their expectations. This study focuses on functional diversity - differences in business practices between foreign and local companies - and its influence on IJV performance. We investigate the influence of this functional diversity on the performance of IJVs and discuss how companies can moderate this influence through adaptation, trust, commitment and communication. Hypotheses are formulated and empirically tested using data gathered through a questionnaire survey of managers of German-Chinese IJVs. The results show that although functional diversity has a negative impact on IJV performance, managers can influence the magnitude of this impact. We use insights from interviews with managers of German-Chinese IJVs in China to supplement our discussion and provide some indication of best practice

The Rising Pitch Metaphor: An Empirical Study.

NoThis paper describes a set of experiments that investigated the use of rising pitch notes to communicate graphical information to visually impaired users. The information communicated in the experiments included coordinate locations within a 40×40 graphical grid, the navigation of an auditory cursor within the graphical grid, the communication of simple graphical shapes and their size. The five simple shapes communicated were rectangles, squares, circles, horizontal and vertical lines. Stereophony, timbre, rhythms, and short tunes were used in addition to the rising pitch metaphor to aid disambiguation. Results suggested that the rising pitch approach enabled visually impaired users to understand the graphical information communicated in the absence of any visual aid. The paper concludes with a discussion of the use of rising pitch metaphor to communicate graphical information

A solid-state NMR study of molecular mobility and phase separation in co-spray-dried protein-sugar particles

NoMolecular mobility and physical form of co-spray-dried sugar:lysozyme formulations were evaluated. Co-spray-dried trehalose:lysozyme and sucrose:lysozyme formulations in 1:9, 1:1 and 9:1 ratios (w:w) were stored at 0% RH and 75% RH for 5-6 days. Molecular mobility and physical form of the co-spray-dried formulations after storage were determined by using 13C and 1H solid-state NMR as well as X-ray powder diffractometry. The results showed that increasing sugar content in co-spray-dried formulations stored at 0% RH decreased molecular mobility of the amorphous formulations indicating a close association of the protein and sugar. Exposure of sugar:lysozyme 1:1 and 9:1 formulations to 75% RH led to separation of sugar and protein phases, where the sugar phase was crystalline. The intimate sugar:lysozyme interaction of the formulations stored at 0% RH and the phase separation of the sugar-rich formulations stored at 75% RH were also confirmed by using 13C solid-state NMR spin-lattice relaxation time-filter (T1-filter) measurements. The propensity of sucrose and trehalose to crystallise was similar; however, the results suggest that part of the sugar in the phase-separated formulations remained amorphous and in close association with lysozyme

Confidentiality and public protection: Ethical dilemmas in qualitative research with adult male sex offenders.

NoThis paper considers the ethical tensions present when engaging in in-depth interviews with convicted sex offenders. Many of the issues described below are similar to those found in other sensitive areas of research. However, confidentiality and public protection are matters that require detailed consideration when the desire to know more about men who have committed serious and harmful offences is set against the possibility of a researcher not disclosing previously unknown sensitive information that relates to the risk of someone being harmed

Modelling the large strain constitutive behaviour of polycarbonate under isothermal and anisothermal conditions

YesWe have studied the tensile behaviour of polycarbonate at large strains below the glass transition temperature. Experiments have been carried out at a series of constant temperatures and also under conditions of falling temperature. The specimens neck with a natural draw ratio of ~2, and the study focuses mainly on the necked material. Isothermal experiments reveal an elastic mechanism that initiates beyond the natural draw ratio. A model consisting of an Eyring process and two Gaussian elastic mechanisms is shown to be applicable to both the isothermal and anisothermal stress relaxation and stress-strain results. The same model also produces reasonable estimates of the stresses generated during the necking process. In addition, a simple relationship between isothermal and anisothermal stress relaxation is demonstrated

Sympathetic innervation of ciliary muscle and oculomotor function in emmetropic and myopic young adults.

NoPurpose: Evidence exists for an additional inhibitory accommodative control system mediated by the sympathetic branch of the autonomic nervous system (ANS). This work aims to show the relative prevalence of sympathetic inhibition in young emmetropic and myopic adults, and to evaluate the effect of sympathetic facility on accommodative and oculomotor function. Methods: Profiling of ciliary muscle innervation was carried out in 58 young adult subjects (30 emmetropes, 14 early onset myopes, 14 late onset myopes) by examining post-task open-loop accommodation responses, recorded continuously by a modified open-view infrared optometer. Measurements of amplitude of accommodation, tonic accommodation, accommodative lag at near, AC/A ratio, and heterophoria at distance and near were made to establish a profile of oculomotor function. Results: Evidence of sympathetic inhibitory facility in ciliary smooth muscle was observed in 27% of emmetropes, 21% of early-onset myopes and 29% of late-onset myopes. Twenty-six percent of all subjects demonstrated access to sympathetic facility. Closed-loop oculomotor function did not differ significantly between subjects with sympathetic facility, and those with sympathetic deficit. Conclusions: Emmetropic and myopic groups cannot be distinguished in terms of the relative proportions having access to sympathetic inhibition. Presence of sympathetic innervation does not have a significant effect on accommodative function under closed-loop viewing conditions

The GAMESS-UK electronic structure package: algorithms, developments and applications.

NoA description of the ab initio quantum chemistry package GAMESS-UK is presented. The package offers a wide range of quantum mechanical wavefunctions, capable of treating systems ranging from closed-shell molecules through to the species involved in complex reaction mechanisms. The availability of a wide variety of correlation methods provides the necessary functionality to tackle a number of chemically important tasks, ranging from geometry optimization and transition-state location to the treatment of solvation effects and the prediction of excited state spectra. With the availability of relativistic ECPs and the development of ZORA, such calculations may be performed on the entire Periodic Table, including the lanthanides. Emphasis is given to the DFT module, which has been extensively developed in recent years, and a number of other, novel features of the program. The parallelization strategy used in the program is outlined, and detailed speedup results are given. Applications of the code in the areas of enzyme and zeolite catalysis and in spectroscopy are described