Medicine in the Medieval North Atlantic World. Vernacular Texts and Traditions

Studies of medical learning in medieval England, Wales, Ireland, and Scandinavia have traditionally focused on each geographical region individually, with the North Atlantic perceived as a region largely peripheral to European culture. Such an approach, however, means that knowledge within this part of the world is never considered in the context of more global interactions, where scholars were in fact deeply engaged in wider intellectual currents concerning medicine and healing that stemmed from both continental Europe and the Middle East. The chapters in this interdisciplinary collection draw together new research from historians, literary scholars, and linguists working on Norse, English, and Celtic material in order to bring fresh insights into the multilingual and cross-cultural nature of medical learning in northern Europe during the Middle Ages, c. 700-1600. They interrogate medical texts and ideas in both Latin and vernacular languages, addressing questions of translation, cultural and scientific inheritance, and exchange, and historical conceptions of health and the human being within nature. In doing so, this volume offers an in-depth study of the reception and transmission of medical knowledge that furthers our understanding both of scholarship in the medieval North Atlantic and across medieval Europe as a whole

Climate change risks illustrated by the Intergovernmental Panel on Climate Change (IPCC) “burning embers”

The completion of the Sixth Assessment Cycle of the Intergovernmental Panel on Climate Change (IPCC) provides a unique opportunity to understand where the world stands on climate-change-related risks to natural and human systems at the global level, as well as for specific regions and sectors. Since its Third Assessment Report (AR3), released 2 decades ago, the IPCC has developed a synthetic representation of how risks increase with global warming, with risk levels reflected by the colours used, including shades of yellow and red, which led to the nickname “burning embers”. While initially designed to illustrate five overarching Reasons for Concern, these diagrams have been progressively applied to risks in specific systems and regions over the last 10 years. However, the information gathered through expert elicitation and the resulting quantitative risk assessments have hitherto remained scattered within and across reports and specific data files. This paper overcomes this limitation by developing a database containing all embers from AR3 to AR6 and an associated online “Climate Risks Embers Explorer” (CREE) to facilitate the exploration of the assessed risks. The data are also available in an archive file in a widely accessible format (https://doi.org/10.5281/zenodo.12626976, Marbaix et al., 2024). Important aspects of data homogenization are discussed, and an approach to structuring information on assessed risk increases is presented. Potential uses of the data are explored through aggregated analyses of risks and adaptation benefits, which show that, excluding high-adaptation cases, half of the assessed risk levels increase from a moderate risk to a high risk between 1.5 and 2 to 2.3 °C of global warming, a result which is consistent with the separate assessment of the Reasons for Concern by the IPCC. The database lays the groundwork for future risk assessments and the development of burning embers by providing a standardized baseline of risk data. It also highlights important areas for improvement in the forthcoming Seventh Assessment Cycle of the IPCC, particularly towards the systematic, homogeneous, and structured collection of information on illustrated risk increases; comprehensive coverage of impacted regions; a systematic consideration of adaptation and/or vulnerability levels; and, possibly, the coverage of risks from response measures. In the context of an ever-growing body of literature and knowledge, the facility described herein has the potential to help in synthesizing and illustrating risks across scales and systems in a more consistent and comprehensive way

Export policy cooperation in a pandemic: the good, the bad and the hopeful

We develop a model in which vaccine‐producing firms from different developed countries supply vaccines to the developing world during a pandemic. Exporting countries experience a negative externality from incomplete global vaccination, which they try to mitigate by exporting vaccines to developing countries. A cooperative export policy is compared to the alternative regimes of non‐cooperation and non‐intervention. When the negative externality is low, cooperation among exporting countries is worse for global welfare than non‐intervention. However, at high externality levels, export policy cooperation is globally superior to non‐cooperative export subsidization. It then even has the potential to maximize global welfare

Mesenchymal stromal cells can block palmitate training of macrophages via cyclooxygenase-2 and interleukin-1 receptor antagonist

Innate training of macrophages can be beneficial for the clearance of pathogens. However, for certain chronic conditions, innate training can have detrimental effects due to an excessive production of pro-inflammatory cytokines. Obesity is a condition that is associated with a range of increased pro-inflammatory training stimuli including the free fatty acid palmitate. Mesenchymal stromal cells (MSCs) are powerful immunomodulators and known to suppress inflammatory macrophages via a range of soluble factors. We show that palmitate training of murine bone-marrow-derived macrophages and human monocyte-derived macrophages (MDMs) results in an increased production of TNFa and IL-6 upon stimulation with lipopolysaccharide and is associated with epigenetic remodeling. Palmitate training led to metabolic changes, however, MSCs did not alter the metabolic profile of human MDMs. Using a transwell system, we demonstrated that human bone marrow MSCs block palmitate training in both murine and human macrophages suggesting the involvement of secreted factors. MSC disruption of the training process occurs through more than one pathway. Suppression of palmitate-enhanced TNFa production is associated with cyclooxygenase-2 activity in MSCs, while secretion of interleukin-1 receptor antagonist by MSCs is required to suppress palmitate-enhanced IL-6 production in MDMs

A Sensitivity Analysis of Wave Energy Converter Model Predictive Control Systems With Wave Excitation Force Estimation and Prediction

Understanding the sensitivity of energy-maximizing control for wave energy converters (WECs), to various model errors, is crucial for application. Many advanced WEC controllers, especially model predictive control (MPC)-like controllers, require estimation and prediction of wave excitation force (WEF). However, previous studies only focus on the controller in isolation, without considering the error coupling effects when a complete estimation–prediction loop is involved. In this study, it is revealed through numerical analysis that the complete MPC system has sensitivity behavior completely different from the isolated MPC; under certain model errors, the system can become particularly unpredictable, exhibiting potential instability and self-locking phenomena, which cannot be observed from the examination of control sensitivity alone. Meanwhile, different tuning options for the WEF estimator and predictor are examined, where the accuracy–robustness tradeoff is shown to be critical for performance amelioration under errors. Based on the analysis, this study challenges the widely assumed “separation principle” of WEF estimation/prediction and WEC control, highlights the importance of incorporating a complete estimation–prediction loop in sensitivity examination, and draws practical guidelines for WEC control application

Is there a global-business-subculture effect on gender differences? A multisociety analysis of subordinate influence ethics behaviors

While business studies on gender have increased, they continue to adopt traditional approaches with limited samples drawn from general populations (e.g., students and teachers). In contrast, we investigate gender differences with our focus solely on business professionals. Specifically, we study 40 societies using the four dimensions of subordinate influence ethics (SIE) behaviors: pro-organizational behaviors, image-management behaviors, self-serving behaviors, and maliciously intended behaviors. We employed crossvergence theory as our theoretical foundation, with its two competing forces, sociocultural (gender differences) and business-ideological (no gender differences), which translates to a global-business-subculture effect. We found no gender differences for three of the four SIE behaviors and minimal differences for the fourth for our sample of business professionals. Thus, our findings differ significantly from those of previous general-population samples. We also tested for societal-level moderating effects of collectivism and individualism using the business values dimensions (BVD) measure. Our individualism findings, the primary values dimension associated with business success, in conjunction with findings from other studies, support our nonsignificant SIE differences findings. In sum, the truly minimal gender differences that we found provide strong support for the perspective that there is a global-business-subculture effect. Our findings also suggest that ethical differences between genders are minimal across the global workforce. We discuss the implications for international business

Spatio-temporal dynamics of speleothem growth and glaciation in the British Isles

Reconstructing the spatio-temporal dynamics of glaciations and permafrost largely relies on surface deposits and is therefore a challenge for every glacial period older than the last due to erosion. Consequently, glaciations and permafrost remain poorly constrained worldwide before ca. 30 ka. Since speleothems (carbonate cave deposits) form from drip water and generally indicate the absence of an ice sheet and permafrost, we evaluate how speleothem growth phases defined by U series dates align with past glacial–interglacial cycles. Further, we make the first systematic comparison of the spatial distribution of speleothem dates with independent reconstructions of the history of the British–Irish Ice Sheet (BIIS) to test how well geomorphologic ice reconstructions are replicated in the cave record. The frequency distribution of 1020 U series dates based on three different dating methods between 300 and 5 ka shows statistically significant periods of speleothem growth during the last interglacial and several interstadials during the last glacial. A pronounced decline in speleothem growth coincides with the Last Glacial Maximum before broad reactivation during deglaciation and into the Holocene. Spatio-temporal patterns in speleothem growth between 31 and 15 ka agree well with the surface-deposit-based reconstruction of the last BIIS. In data-rich regions, such as northern England, ice dynamics are well replicated in the cave record, which provide additional evidence about the spatio-temporal distribution of permafrost dynamics. Beyond the Last Glacial Maximum, the distribution of speleothem dates across the British Isles offers the opportunity to improve chronological constraints on past ice sheet variability, with evidence for a highly dynamic Scottish ice sheet during the last glacial. The results provide independent evidence of ice distribution complementary to studies of surface geomorphology and geology, and the potential to extend reconstructions into permafrost and earlier glacial cycles. Whilst undersampling is currently the main limitation for speleothem-based ice and permafrost reconstruction even in relatively well-sampled parts of the British Isles, we show that speleothem dates obtained using modern mass spectrometry techniques reveal a higher spatio-temporal resolution of glacial–interglacial cycles and glacial extent than previously possible. Further study of leads and lags in speleothem growth compared to surface deposition may provide new insights into landscape-scale dynamics during ice sheet growth and retreat

BioBeo

This song is part of the BioBeo Education Programme, designed to introduce primary school children to the concept of the circular bioeconomy in a fun and engaging way. It aligns perfectly with the AgroCycle Kids Education Programme, developed by Dr Máire Nic an Bhaird and Dr Laoise Ní Chléirigh at Maynooth University, which emphasises participatory, hands-on learning. The BioBeo song encourages children to explore ideas of sustainability and circularity. By incorporating this song into classroom activities, educators can foster creativity and critical thinking about environmental solutions. It’s an excellent resource for making bioeconomy concepts accessible and enjoyable for young learners

Deepening dialogue in Silent Spaces: An exploration of pedagogical informed practice in adult and community education spaces within communities in contention.

The rise of political populism has posed significant challenges for democratic societies and for the academy. Populist movements often emphasise a division between ‘the people’ and ‘the elite’, pushing narratives that thrive on polarisation. In such contexts dialogue between social and community groups and populist movements is crucial for the health of democracy. However, within the academy, and specifically within adult and community education in formal, informal, and non-formal spaces, populism tends to undermine the practice of dialogue by promoting exclusionary practices, rejecting, and indeed silencing the legitimacy of opposing views. This article explores the theoretical foundations of dialogue and silence as critical components of communicative discourse. It posits the theories of Freire (1970, 1996, 1998, 2010), Greene (1973, 1978, 1995), Brookfield (1995, 2009), Lederach (2003), Bar-on (1989, 2007), and Giroux (2005) as a means of scaffolding a collaborative theoretical framework for conducting meaningful dialogue amongst and between communities in contention. In doing so it aims to offer practitioners of adult and community education a conceptual framework to support participatory dialogue that engages with contentious and complex narratives. This article offers the concept of silence as a societal response to conflict, the construct of dialogue as one means to deconstruct the silence, the acknowledgement of truth being multifaceted, and the complexity that arises in dealing with identity in communities in conflict, where the practice of dialogue is challenging, elusive, and subdued. In concluding, it suggests where arts-based methodologies form the backdrop, there is hope for shared understanding to emerge organically

Civic Engagement in the Neoliberal-Patriarchal University: Lessons from Irish Practitioners Working Within and Against the System.

This study examines civic engagement and highlights the ways community engagement practice can learn from practitioners in Ireland as they navigate present-day university environments. It explores the origins, interpretations, and common operational models of civic engagement, presenting it as a contested field shaped by differing orientations and politics. I delve more deeply into community engagement practices on the continuum from transactional to transformative, making the case for the latter throughout. I also explore how the relevant Irish civic engagement policies are enabling and restricting for practitioners, and how they may contribute to the domestication of community engagement within the neoliberal-patriarchal university. This research is positioned within the context of the neoliberal-patriarchal framing of the Irish higher education system, and conducted within a critical feminist research paradigm, drawing from the theories of intersectionality, critical feminist pedagogy, as well as my own practice in community engagement. It is a qualitative study that consists of in-depth interviews with seven Irish female civic engagement practitioners. The findings reveal that the participants’ commitments are to a radical and transformative model of civic engagement focused on social justice and equality, and based on the principles of holistic, engaged and nurturing pedagogy. At the same time, this study shows that the practice tends to be more traditional and tempered. This research portrays community engagement as innovative work in a rigid higher education system, and a practice that is liminal and largely invisible and unrecognised. Despite its marginal status, this research also documents the ways in which civic engagement can disturb the dominant discourse of a neoliberal-patriarchal university. The unique contribution of this research lies in its focus on the lived experiences of civic engagement practitioners, offering a new perspective on community engagement through a critical, intersectional feminist lens. It sheds light on the values, practices, and challenges faced by practitioners who work in a university environment that is often counter-normative to their practice and values, expanding our understanding of civic engagement in Ireland