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This is an update request for the document Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation by Ming Tang, Bo Chen, Tong Lin, Zhaozhong Li, Carolina Pardo, Christine Pampo, Jing Chen, Ching-Ling Lien, Lizi Wu, Lingbao Ai, Heiman Wang, Kai Yao, S. Paul Oh, Edward Seto, Lois E. H. Smith, Dietmar W. Siemann, Michael P. Kladde, Constance L. Cepko and Jianrong Lu

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