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This is an update request for the document Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death by Kuei-Hua Chang, Parminder Singh Multani, Kai-Hui Sun, Fabien Vincent, Yolanda de Pablo, Soumitra Ghosh, Ritika Gupta, Hyun-Pil Lee, Hyoung-gon Lee, Mark A. Smith and Kavita Shah

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