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This is an update request for the document Interleukin-1α treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2 by Angelika K. Lemke, John D. Sandy, Henning Voigt, Rita Dreier, Jennifer H. Lee, Alan J. Grodzinsky, Rolf Mentlein, Jakob Fay, Michael Schunke and Bodo Kurz

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