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This is an update request for the document Added value of combining methotrexate with a biological agent compared to biological monotherapy in rheumatoid arthritis patients:A systematic review and meta-analysis of randomised trials by S. Tarp, T.S. Jørgensen, D.E. Furst, A. Dossing, P.C. Taylor, E.H. Choy, M.E. Suarez-Almazor, A. Lyddiatt, L.E. Kristensen, H. Bliddal and R. Christensen

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