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This is an update request for the document Interferon regulatory factor 5 genetic variants are associated with cardiovascular disease in patients with rheumatoid arthritis by Mercedes García-Bermúdez, Raquel López-Mejías, Fernanda Genre, Santos Castañeda, Javier Llorca, Carlos González-Juanatey, Alfonso Corrales, Begoña Ubilla, José A Miranda-Filloy, Trinitario Pina, Carmen Gómez-Vaquero, Luis Rodríguez-Rodríguez, Benjamín Fernández-Gutiérrez, Alejandro Balsa, Dora Pascual-Salcedo, Francisco J López-Longo, Patricia Carreira, Ricardo Blanco, Javier Martín and Miguel A González-Gay

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