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This is an update request for the document Prospective study on the mismatch concept in acute stroke patients within the first 24 h after symptom onset - 1000Plus study by Benjamin Hotter, Sandra Pittl, Martin Ebinger, Gabriele Oepen, Kati Jegzentis, Kohsuke Kudo, Michal Rozanski, Wolf U Schmidt, Peter Brunecker, Chao Xu, Peter Martus, Matthias Endres, Gerhard J Jungeh├╝lsing, Arno Villringer and Jochen B Fiebach

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