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This is an update request for the document Family of Enhanced Photoacoustic Imaging Agents for High-Sensitivity and Multiplexing Studies in Living Mice by Adam de la Zerda (1482949), Sunil Bodapati (2070958), Robert Teed (2070961), SalomoĢn Y. May (2070964), Scott M. Tabakman (438868), Zhuang Liu (551357), Butrus T. Khuri-Yakub (475821), Xiaoyuan Chen (322516), Hongjie Dai (357638) and Sanjiv S. Gambhir (1234206)

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